Primary aldosteronism(PA)is a disorder of aldosterone hypersecretion leading to sodium retention,potassium loss,increased blood volume and suppression of renin,characterized by hypertension with or without hypokalemia.PA is usually diagnosed between the ages of 30 and 50,and cases in children are rare.This article presents a child aged four years and eleven months who was admitted to hospital with markedly elevated aldosterone levels.The symptoms of hyper-tension and hypokalemia were not obvious,and whole exome sequencing of peripheral blood showed a normal result.Lat-er,a partial adrenalectomy was performed.The postoperative pathology of the adrenal gland showed cortical hyperplasia,and whole exome sequencing of the adrenal gland showed no obvious mutations.Finally,this young patient was consid-ered to have primary hyperaldosteronism caused by adrenal cortical hyperplasia.
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