Latent class analysis of symptom characteristics of nasopharyngeal carcinoma patients receiving intensity modulated radiation therapy during rehabilitation periodone
Latent class analysis of symptom characteristics of nasopharyngeal carcinoma patients receiving intensity modulated radiation therapy during rehabilitation periodone
Objective To understand the current status of symptom distress and potential categories of symptom charac-teristics in nasopharyngeal carcinoma patients after radiation therapy by a one-year follow-up of symptoms in nasopharyn-geal carcinoma patients after intensity-modulated radiation therapy,and to explore the differences in symptom characteris-tics among different types of patients to provide strategies for clinical nurses to develop targeted and sustained symptom management.Methods Nasopharyngeal carcinoma patients undergoing intensity-modulated radiation therapy and com-pleting radiation therapy after one year were selected in Zhejiang Cancer Hospital from January 2020 to December 2022.General information questionnaire and QLQ.H&N35 were utilized as the investigating tools.Latent class analysis(LCA)was used to explore the latent classes of the symptom characteristics of nasopharyngeal carcinoma patients,and the gener-al characteristics of different types of patients were analyzed.Results A total of 156 patients were selected.The symp-toms with a high incidence rate were hyposexuality(52.6％),dry mouth(50.6％),and dental problems(39.7％)one year after radiotherapy in nasopharyngeal carcinoma patients.Among them,the severity of dry mouth[2.00(1.0,2.0)points]and hyposexuality[1.5(1.0,2.0)points]were higher.The symptom characteristics of nasopharyngeal carcinoma patients could be divided into three latent classes,which were named low symptom response group(77.56％),high physical symptoms response group(12.18％),and emotional psychological distress group(10.26％).One-way ANOVA showed that there were significant differences in education level,BMI,and radiation therapy methods among the three types.Conclusion The symptoms of nasopharyngeal carcinoma patients receiving intensity-modulated radiation therapy during home rehabilitation include three latent classes.Medical workers should identify the latent class to provide continuous symptom follow-up management and psychological counseling intervention for patients,reduce the physical and mental symptoms of patients and psychological counseling interventions,improve the quality of life of pa-tients during home rehabilitation,and promote rehabilitation.
关键词
鼻咽癌/调强放疗/症状特征/潜在类别分析
Key words
Nasopharyngeal carcinoma/Intensity modulated radiation therapy/Symptom characteristics/Latent class analysis
维普
万方数据