Objective Polydontia is a common disease in which the number of teeth increases due to abnormal tooth de-velopment.Clinically,polydontia can be classified into syndromic and non-syndromic types based on whether it is associ-ated with systemic diseases,with the former being rare.This study discusses the clinical characteristics,imaging find-ings,and treatment methods of non-syndromic polydontia in the anterior maxillary region,providing references and a ba-sis for clinical diagnosis,treatment,and research.Methods A total of 395 patients with polydontia in the anterior max-illary region treated at the Department of Oral and Maxillofacial Surgery of Anhui Medical University Affiliated Stomatolog-ical Hospital from January 2019 to June 2023 were selected.Retrospective analysis was conducted on the patients'per-sonal data,clinical manifestations,imaging examinations,surgical plans,etc.Statistical analysis of the data was per-formed using SPSS 22.0 software.Results This study included 395 patients with polydontia in the anterior maxillary re-gion,totaling 551 supernumerary teeth.The number of male patients was higher than that of female patients,with 293 male patients and 102 female patients,a male-to-female ratio of 2.87:1.The ages of the patients ranged from 3 to 45 years old.Single supernumerary teeth were the most common,with 256 cases,accounting for 64.81%.Most patients presented during the mixed dentition period,with 251 cases,accounting for 63.54%.The most common shapes of super-numerary teeth were conical and nodular,totaling 529 teeth,accounting for 96.01%.The most common positional rela-tionship with adjacent teeth was inversion,with 264 teeth,accounting for 47.91%.The most common surgical approach was through the palatal side,with 292 cases,accounting for 73.92%.Conclusion Non-syndromic maxillary anterior teeth are asymptomatic,with a few clinical manifestations such as impacted teeth and widened dental space,and are more common in children during their transitional period.Male patients are more common than female patients.High impacted teeth are the most common,and the palatal approach is often used for surgery.