Clinical study on treating chronic heart failure of Qi deficiency and blood stasis type with modified Yangxin Decoction and Guan's ear needle combination therapy
Objective To observe the effects of modified Yangxin Decoction combined with Guan's ear needle on heart function,activity endurance,Chinese medicine syndrome,and clinical efficacy in patients with chronic heart failure(CHF),and to explore the mechanism by which this combination improves these parameters in CHF patients.Methods During the period from January to December 2021,100 patients with Qi deficiency and blood stasis type CHF were treated at the Internal Medicine Clinic.They were randomly divided into an observation group and a control group using a single-blind protocol.Finally,48 patients in the observation group and 47 patients in the control group were completed.Both groups of patients were given basic treatment.The control group received routine western medicine treatment,including car-diac strengthening,diuresis,and vasodilation.The observation group received a combination of modified Yangxin Decoction and Guan's ear needle treatment in addition to the control group.Changes in Chinese medicine syndromes,cardiac func-tion,activity endurance,N-terminal prohormone of brain natriuretic peptide(NT-proBNP)levels,and cardiac ultrasound were observed before and after treatment in two groups of patients.The clinical efficacy of the two groups was then com-pared.Results After treatment,the Chinese medicine syndrome score,NT-proBNP level,and Lee's heart failure score in the observation group were significantly lower than those in the control group,and the activity endurance was significantly improved compared to the control group(P＜0.05).The left ventricular end-diastolic diameter(LVEDD),left ventricular end-systolic diameter(LVESD),left ventricular mass index(LVMI),and interventricular septal thickness(IVST)in the observation group were significantly decreased,while left ventricular ejection fraction(LVEF)was significantly increased compared to the control group(P＜0.05).The total effective rate of the observation group was 93.8％(45/48),signifi-cantly higher than the 78.7％(37/47)in the control group(P＜0.05).Conclusion The combination of modified Yangx-in Decoction and Guan's ear needle can significantly improve the clinical efficacy for CHF patients.It effectively improves their Chinese medicine syndrome,activity endurance,and heart function,increases LVEF,and reduces LVEDD,LVESD,LVMI,IVST,and NT proBNP levels.
维普
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