The application of low-temperature hand and foot covers combined with"five precautions"education in the prevention of taxane-related peripheral neuropathy
Objective To explore the application effect of non-pharmacological intervention in the prevention of taxane-related peripheral neuropathy.Methods A total of 252 patients who were hospitalized in the Department of Oncology of the First Affiliated Hospital of Bengbu Medical University and received taxane-based chemotherapy were selected as the study subjects.Among them,125 patients from July to December 2022 were taken as the control group,and 127 patients from January to June 2023 were taken as the observation group.Patients in the control group received routine chemothera-py care from the medical oncology department,while patients in the observation group received low-temperature hand and foot covers combined with"five precautions"education.The peripheral neuropathy including symptom experience,quali-ty of daily life,and adverse home safety events between the two groups were compared.Results The incidence,severi-ty,and degree of symptom distress of finger/hand numbness,toe/foot numbness,toe/foot tingling,finger/hand or toe/foot discomfort,and muscle or joint pain in the observation group were lower than those in the control group(P＜0.05).The observation group had lower rates of holding small items[38.58％(49/127)],sleeping[46.46％(59/127)],writing[55.91％(71/127)],and doing household chores[62.99％(80/127)]compared to the control group[52.00％(65/125),61.60％(77/125),69.60％(87/125),82.40％(103/125),P＜0.05].The incidence of home falls(5.51％,7/127)and collisions(7.87％,10/127)in the observation group were lower than those in the con-trol group[16.00％(20/125)and 18.40％(23/125),P＜0.05].Conclusion The use of low-temperature hand and foot covers in combination with"five precautions"education can effectively reduce the occurrence of taxane-related pe-ripheral neuropathy,improve patients'symptom experience and quality of daily life,and reduce the occurrence of adverse home safety events.
Low temperature hand and foot covers"Five precautions"educationTaxanesPeripheral neuropathy
万方数据
