Objective To explore the high-risk factors of severe Mycoplasma pneumoniae pneumonia(SMPP)in chil-dren,and analyze the diagnostic value of C-reactive protein(CRP),D-dimer(D-D),and lactate dehydrogenase(LDH)in SMPP.Methods Retrospective analysis of clinical data of 320 children with Mycoplasma pneumoniae pneumonia ad-mitted to the First Affiliated Hospital of the University of Science and Technology of China from June 2023 to November 2023.According to the severity of the condition,they were divided into 85 cases of general Mycoplasma pneumoniae pneumonia(GMPP)and 235 cases of SMPP.Two groups were subjected to univariate analysis,and factors with statisti-cal differences were included in multivariate logistic regression analysis.Draw ROC curves were performed to analyze the diagnostic value of laboratory indicators for SMPP.Results The SMPP group had a longer fever and cough times than the GMPP group,and CRP,platelets,platelet volume,fibrinogen,D-D,fibrinolytic products,alanine aminotrans-ferase,serum total bilirubin,γ-Glutamyl transpeptidase,and LDH were higher in the GMPP group than those in the GMPP group(P＜0.05).Multivariate logistic regression analysis showed that CRP,D-D,and LDH were independent risk factors for the occurrence of SMPP,with OR(95％CI)of 1.049(1.008-1.092),18.674(4.184-83.336),and 1.007(1.001-1.013).ROC curve analysis showed that when the critical values of D-D and LDH were set at 0.69μg/mL and 291.45 U/L,the sensitivity and specificity for identifying SMPP were 51.5％and 91.8％,63.0％and 69.4％,respectively.Conclusion Elevated levels of CRP,D-D,and LDH are independent risk factors for the occur-rence of SMPP,among which D-D and LDH have important clinical value in the diagnosis of SMPP.
维普
万方数据
