Objective To evaluate the suitability and safety of autologous blood clot technique in flexible ureteroscopy combined with the holmium laser lithotripsy.Methods A retrospective analysis of 65 patients with ureteral calculi in the First Affiliated Hospital of Bengbu Medical University who underwent flexible ureteroscopy combined with the holmium la-ser lithotripsy was performed from June 2022 to February 2024.They were divided into two groups according to whether autologous blood clot technology was used or not:30 cases in observation group and 35 cases in control group.The opera-tive duration,the number of stone removal during operation,duration of hospital stay,the number of residual 2 mm stones,the number of residual 4 mm stones and complications were recorded for statistical analysis.Results There were no significant differences in age,sex,BMI,stone number,stone location and cumulative stone size between the two groups(P＞0.05).The operation time of the observation group[(54.97±7.06)min]was shorter than that of the con-trol group[(68.14±9.75)min],the number of intraoperative stone removal[(11.50±3.04)times]was significantly less than that of the control group[(20.77±3.36)times],and the number of cases of residual 2 mm stones after opera-tion(8 cases)was significantly less than that of the control group(22 cases),and the differences were all statistically significant(P＜0.05).The number of residual 4 mm stones,duration of hospital stay and complications were insignifi-cantly different(P＞0.05).Conclusion The use of autologous blood clot technique has good applicability and safety in flexible ureteroscopy combined with the holmium laser lithotripsy.It could shorten the operation time,reduce the number of stone removal during operation,improve the postoperative stone free rate,and minimize the incidence of clinically in-significant residual fragments,potentially reduce stone recurrence.
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