Objective This study analyzes the clinical outcomes of the combined application of 3D-printed titanium alloy intervertebral fusion devices and autologous bone treated with platelet-rich plasma(PRP)in anterior cervical discectomy and fusion(ACDF)procedures.It further assesses the potential benefits of this combination in promoting spinal stability and vertebral fusion.Methods From August 2021 to May 2023,110 patients with cervical spondylosis who needed AC-DF were selected.Among them,56 patients with 3D printed interbody fusion cage were classified as Group A,and 54 patients with 3D printed interbody fusion cage combined with PRP allograft were classified as Group B.The operation time,intraoperative blood loss,postoperative drainage,Japanese Orthopedic Association(JOA)score,and visual simu-lated pain(VAS)score were observed,and the segmental angle(SA),cervical curvature index(CCI),intervertebral disc height(IH)and the fusion rate at each time point after operation were measured.Results There was no significant difference in operation time and blood loss between the two groups(P＞0.05),and the postoperative drainage in group B was significantly less than that in group A(P＜0.05).There were statistical differences in VAS score and JOA score e-valuated at different times(P＜0.05).There were statistical differences in SA,CCI,and IH measured at different times(P＜0.05).The X-ray of the cervical spine showed that the imaging fusion rates of group A and group B were 48.21％(27/56)and 70.37％(38/54)at 3 months after operation,73.21％(41/56)and 92.59％(50/54)at 6 months after operation,and 100.00％at 12 months after operation.The fusion rates of group B at 3 months and 6 months after opera-tion were significantly higher than those of group A(P＜0.05).Conclusion The use of a 3D printed interbody fusion cage combined with PRP-containing allogenic bone in ACDF has the advantage of less postoperative drainage,which can also promote early fusion and improve the success rate of fusion surgery.
维普
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