Observation on the efficacy of He's Yiqi Yangxue Decoction in regulating the placenta previa state of spleen and kidney qi deficiency
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维普
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目的 探讨何氏益气养血束胞饮不同使用方法对脾肾气虚型胎盘前置状态的临床疗效.方法 收集2020年1月-2022年12月在宁波市妇女儿童医院中医科就诊的脾肾气虚型胎盘前置状态患者90例,按随机数字表法分为治疗组A、治疗组B、对照组,每组30例.对照组予期待疗法,治疗组A予何氏益气养血束胞饮内服,治疗组B予何氏益气养血束胞饮联合穴位贴敷治疗.比较3组患者的综合疗效、中医证候评分、28周时胎盘位置情况与妊娠、新生儿结局.结果 (1)综合疗效:治疗1个疗程后,治疗组B总有效率为86.67％(26/30),与治疗组A(53.33％,16/30)和对照组(36.67％,11/30)比较,差异有统计学意义(P＜0.017);治疗2个疗程后,治疗组B总有效率为96.67％(29/30),治疗组A为93.33％(28/30),2组比较差异无统计学意义(P＞0.017).(2)中医症候积分:治疗2个疗程后,治疗组A和治疗组B中医症候积分均低于对照组(P＜0.01)o(3)28周胎盘位置情况:治疗组A和治疗组B有效率均为96.67％(29/30),与对照组(66.67％,20/30)比较,差异有统计学意义(P＜0.017).(4)妊娠与新生儿结局:治疗组A和治疗组B产后24 h出血量低于对照组,新生儿体质量、新生儿1 min Apgar评分均高于对照组(P＜0.05).结论 何氏益气养血束胞饮可有效改善脾肾气虚型孕妇的胎盘前置状态,提升胎盘位置,改善临床症状,改善妊娠结局与新生儿结局,且联合穴位贴敷疗效更优,并能加快治疗进程,值得临床推广应用.
Objective To explore the clinical effects of different methods using He's Yiqi Yangxue Decoction on placenta previa in spleen and kidney qi deficiency.Methods A total of 90 patients diagnosed with placenta previa due to spleen and kidney qi deficiency in Department of Traditional Chinese Medicine,Ningbo Women and Children's Hospital from January 2020 and December 2022.These patients were randomly assigned into three distinct groups:treatment group A,treatment group B,and a control group,each containing 30 individuals.Those in the control group received conservative management therapy.The treatment group A was given He's Yiqi Yangxue Decoction.On the basis of treatment group A,acupoint application was applied to treatment group B.The comprehensive curative effect,TCM symptom score,placental position at 28 weeks,pregnancy and neonatal outcomes were observed in the three groups.Results(1)Comprehensive curative effect:After completing one period of treatment,the number of treatment group B was 86.67％(26/30)in terms of cure rate,which was statistically significant compared with 53.33％(16/30)of treatment group A and 36.67％(11/30)of control group(P＜0.017).After two treatment cycles,the total effective rate was 96.67％(29/30)in treat-ment group B and 93.33％(28/30)in treatment group A,and none distinction in statistics was between them(P＞0.017).(2)TCM symptom score:After two treatment cycles,among treatment group A,treatment group B and control group,the distinction in statistics was significative(P＜0.01).(3)The effective rate of treatment group A and treatment group B was 96.67％(29/30),compared with the control group[66.67％(20/30)],the distinction in statistics was significative(P＜0.017).(4)Regarding pregnancy and neonatal outcomes:Pregnant women's postpartum hemorrhage in 24 hours who were assigned to these two treatment groups were both less than those who were assigned to the control group,and their neonatal body mass and neonatal 1min Apgar score were exceed than those who were assigned to the con-trol group(P＜0.05).Conclusion He's Yiqi Yangxue Decoction can effectively improve the placental previa,improve the position of the placenta,treat clinical symptoms,and improve pregnancy outcomes and neonatal outcomes in pregnant women with spleen and kidney qi deficiency.
Placenta previaHe's Yiqi Yangxue DecoctionSpleen and kidney qi deficiencyAcupoint application
维普
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