Objective Delayed weaning and difficult weaning of mechanical ventilation are the difficulties in the treat-ment of patients with severe craniocerebral injury.This paper aims to shorten the mechanical ventilation time of such pa-tients by analyzing the application value of airway resistance and static lung compliance in ventilator offline screening.Methods Seventy-eight patients with severe craniocerebral injury admitted to the First Ward of ICU at Bozhou People's Hospital from January 2023 to November 2023 were selected and randomly divided into an experimental group(n=39)and a control group(n=39).All patients received dehydration therapy to reduce intracranial pressure,maintain cerebral perfusion,nutritional support,aerosol expectoration,sedation and analgesia,as well as other treatments.The control group underwent traditional ventilator weaning screening method while the experimental group underwent traditional venti-lator weaning screening method based on airway resistance(Raw)≤10 cmH2O·L-1·s-1 and static lung compliance ≥40 mL/cmH2O.The ICU length of stay,ventilator duration,number of spontaneous breathing trial,48 h ventilator re-up rate,incidence of ventilator-associated pneumonia(VAP),total length of hospitalization,and total healthcare expendi-ture were compared between the two groups.Results The length of ICU stay was 11(6,16)days in the experimental group,which was shorter than that in the control group[13(15,19)days,P＜0.05].The duration of mechanical ven-tilation was 141(46,230)hours in the experimental group,which was shorter than that in the control group[212(151,254)hours,P＜0.05].The number of spontaneous breathing trials(SBT)in the experimental group was less than that in the control group[1(1,1)vs.2(1,3),P＜0.05].The total length of hospital stays of the experimental group was shorter than that of the control group[29(20,44)d vs.41(32,62)d,P＜0.05].Additionally,there were lower total medical costs as well as reduced incidence rates of VAP,and re-hospitalization within 48 hours observed among patients from the experimental group compared to those from the control group(P＜0.05).Conclusion Airway resistance and lung compliance measurement combined with traditional ventilator weaning screening method is more conducive to ventila-tor weaning in patients with severe craniocerebral injury,shortening the duration of ventilator use and ICU stay,and re-ducing the total length of hospital stay and medical costs,and reduce the incidence of VAP.
Severe craniocerebral injuryVentilator weaningAirway resistanceStatic lung compliance
维普
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