Objective To analyze the screening and identification results of irregular antibodies in patients with blood transfusion,and to explore the relationship between irregular antibodies and gender,blood transfusion history,and preg-nancy history.Methods The screening and identification results of irregular antibodies in 39 671 transfusion patients from January 2021 to December 2022 were obtained from the hospital electronic medical record system.The number of positive cases for irregular antibodies was recorded,the distribution of irregular antibodies was analyzed,and the relation-ship between the positive rate and specificity of irregular antibodies and patient gender,transfusion history,and pregnan-cy history was explored.Results Among the 39 671 transfusion patients,a total of 365 cases tested positive for irregular antibodies,with a positivity rate of 0.92％.Among them,the highest proportion was positive antibodies in the Rh blood type system(213 cases,accounting for 58.36％).The data showed that among the 365 patients with positive irregular antibodies,females(228 cases,62.47％)had a higher proportion than males(137 cases,37.53％),and the positivity rate of Rh blood type system antibodies in female patients(143 cases,62.72％)was significantly higher than that in males(70 cases,51.09％;P=0.037).Patients with a history of transfusion and those with a history of pregnancy were more likely to have positive Rh blood type system antibodies(P＜0.05).Conclusion Women,blood transfusion history and pregnancy history will increase the probability of positive results on irregular antibody screening.While irregular anti-body screening and identification for patients who have conventional transfusion therapy are carried out,the detection for women,patients with blood transfusion history or pregnancy history should be especially strengthened.
Irregular antibodiesBlood transfusionRh blood group system
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