首页|盆底治疗仪辅助阴道内中药对盆腔炎患者的炎症及激素水平的影响

盆底治疗仪辅助阴道内中药对盆腔炎患者的炎症及激素水平的影响

Impact of pelvic floor therapeutic instrument assisted with traditional Chinese medicine on inflammation and hormone levels in patients with pelvic inflammatory disease

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目的 分析盆底治疗仪辅助阴道内中药对慢性盆腔炎(CPID)患者的炎症及激素水平的影响,为CPID的治疗提供更为充分的理论依据.方法 以2020年3月-2023年10月期间杭州市第三人民医院收治的90例CPID患者为研究对象,按照治疗方式的不同分为中药灌肠组与阴道内治疗组各45例.2组均给予盆底治疗仪治疗,接受中药灌肠的为中药灌肠组,接受阴道内治疗的为阴道内治疗组.比较2组患者临床疗效、炎症水平、激素水平以及不良反应发生率.结果 治疗结束后,阴道内治疗组总有效率(91.11%,41/45)高于中药灌肠组(75.56%,34/45,P<0.05);阴道内治疗组TNF-a、CRP低于中药灌肠组(P<0.05),IL-2、IL-4水平高于中药灌肠组(P<0.05);阴道内治疗组促卵泡生成素(FSH)低于中药灌肠组,雌二醇(E2)高于中药灌肠组(P<0.05);阴道内治疗组卵巢动脉和子宫动脉搏动指数(PI)高于中药灌肠组,阻力指数(RI)低于中药灌肠组.结论 盆底治疗仪辅助阴道内中药治疗CPID患者,可降低炎症因子水平,调节体内激素水平,改善血流动力学水平,提高临床疗效.
Objective To analyze the effects of pelvic floor therapeutic instrument assisted with traditional Chinese medi-cine in vagina on inflammation and hormone level of patients with chronic pelvic inflammatory disease(CPID),so as to provide more sufficient theoretical basis for the treatment of CPID.Methods Ninety patients with CPID admitted to Hangzhou Third People's Hospital from March 2020 to October 2023 were divided into two groups according to different treatment methods:the enema group with traditional Chinese medicine and the vaginal treatment group,with 45 patients in each group.Both groups were treated with pelvic floor therapeutic instrument,with the enema group also receiving tra-ditional Chinese medicine via enema and the intravaginal group receiving it vaginally.The clinical efficacy,inflammation levels,hormone levels,and incidence of adverse reactions were compared between the two groups.Results After treat-ment,the total effective rate in the vaginal treatment group(91.11%,41/45)was higher than that in the enema group(75.56%,34/45,P<0.05).Tumor necrosis factor-α and CRP levels in the vaginal treatment group were lower than those in the traditional Chinese medicine enema group(P<0.05),while the levels of interleukin-2 and interleukin-4 were higher(P<0.05).Follicle-stimulating hormone levels in the vaginal treatment group was lower than that in the tra-ditional Chinese medicine enema group,and estradiol was higher(P<0.05).Additionally,proteasome inhibitor levels of ovarian artery and uterine artery in the vaginal treatment group were higher than that in the traditional Chinese medicine enema group,and resistance index was lower compared to the enema group.Conclusion Pelvic floor therapeutic instru-ment assisted with vaginal Chinese medicine can reduce the level of inflammatory factors,regulate hormones levels,im-prove the level of hemodynamics,and enhance the clinical efficacy in the treatment of CPID.

Pelvic inflammatory diseasePelvic floor therapeutic instrumentIntravaginal treatmentInflammatory fac-torsSerum sex hormone

杨丽青、詹宏

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杭州市第三人民医院妇产科,浙江杭州 310009

浙江大学医学院附属妇产科医院教学部,浙江杭州 310000

盆腔炎 盆底治疗仪 阴道内治疗 炎症因子 血清性激素

浙江省自然科学基金项目杭州市生物医药和健康产业发展扶持科技专项

LQ20H040006WJCY319

2024

中华全科医学
中华预防医学会,安徽省全科医学会

中华全科医学

CSTPCD
影响因子:1.688
ISSN:1674-4152
年,卷(期):2024.22(9)