This article reports a case of hypothyroidism caused by roxadustat,a prolyl-hydroxylase inhibitor,used to treat renal anemia.An 86-year-old male with a 10-year history of chronic renal insufficiency with reduced speech and food in-take for 3 weeks.After 4 months of medication,symptoms of hypothyroidism and abnormal laboratory tests appeared.Af-ter discontinuing roxadustat for one week,his thyroid function gradually normalized.For patients receiving roxadustat treatment,regular thyroid function monitoring is essential,and discontinuation or thyroid hormone replacement therapy should be considered if necessary.
维普
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