Objective To examine the clinical characteristics and potential risk factors associated with systemic lupus er-ythematosus(SLE)patients with cardiovascular diseases.The findings of this study will contribute to the development of more accurate clinical diagnosis and treatment strategies for SLE patients with cardiovascular diseases.Methods The clinical data of 202 patients with SLE,comprising 22 males and 180 females,were collected from the Rheumatology De-partment of the First Affiliated Hospital of Bengbu Medical University between December 2021 and December 2022.The patients were divided into two groups:a case group comprising 58 patients with cardiovascular diseases and a control group comprising 144 patients without cardiovascular diseases.The clinical data of the two groups were subjected to anal-ysis and comparison.Results There were a total of 58 SLE patients with cardiovascular diseases,with an incidence rate of 28.7％.There were statistically significant differences in age,left common carotid artery resistance index,left common carotid artery maximum blood flow velocity,blood glucose,platelet count,IgG level,C3,total cholesterol,D-dimer,an-tiphospholipid antibody positive rate,and disease duration between the two groups(P＜0.05).Logistic regression analy-sis showed that increased age,elevated left common carotid artery resistance index,hyperglycemia,platelet count,and abnormal IgG level were independent risk factors for SLE patients with cardiovascular diseases(P＜0.05).Conclusion The incidence rate of SLE patients with cardiovascular diseases is influenced by multiple factors,among which age in-crease,positive antiphospholipid antibody status,elevated left common carotid artery resistance index,abnormal blood glucose,platelet count,and abnormal IgG level are potential risk factors.It is therefore recommended that these factors should be taken into account in clinical practice in order to develop comprehensive risk assessment and management strat-egies which will effectively reduce the risk of cardiovascular disease in patients with SLE.
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