The efects of fire acupuncture combined with Zishen Qinggan Decoction on recovery progress,body inflammation and risk of PHN in patients with acute herpes zoster
Objective To observe the therapeutic effect of fire acupuncture combined with Zishen Qinggan Decoction on acute herpes zoster and the occurrence of postherpetic neuralgia(PHN).Methods From January 2022 to September 2023,100 patients with acute herpes zoster in the moxibustion Department of Chengde Hospital of Traditional Chinese Medicine were divided into the observation group(n=50,fire acupuncture combined with Zishen Qinggan Decoction)and the control group(n=50,fire acupuncture)by random number table method.The therapeutic effect,traditional Chinese medicine(TCM)syndrome scores,recovery progress,inflammatory indicators[interleukin(IL-2),IL-8,IL-10],and PHN risk were compared.Results The total effective rate in the observation group was higher(88.00％vs.72.00％,P＜0.05),and the scores of TCM syndrome were lower(P＜0.05).Analgesic time[(2.95±0.46)d vs.(3.57±1.02)d],herpes stopping time[(3.77±0.93)d vs.(4.69±1.47)d],and crusting time[(7.80±1.18)d vs.(8.36±0.61)d]in the observation group was shorter(P＜0.05).After treatment,the serum IL-2 concentration in the observation group was higher(P＜0.05),and the serum IL-8 and IL-10 concentrations were lower(P＜0.05).No adverse reactions occurred in both groups.The incidence of PHN at 1 month(12.00％vs.28.00％,X2=4.000,P=0.046)and 2 months(6.00％vs.20.00％,x2=4.332,P=0.037)in the observation group was lower than that in the control group.Conclusion Fire acupuncture combined with Zishen Qinggan Decoction can significantly improve the treatment effect of patients with acute herpes zoster,relieve symptoms,and reduce the incidence of PHN.
NETL
NSTL
万方数据
