Objective To analyze the influencing factors of sleep disorders in lung cancer chemotherapy patients and de-velop nursing strategies to reduce the risk of sleep disorders in lung cancer chemotherapy patients.Methods A total of 110 lung cancer patients admitted to the First Affiliated Hospital of Nanchang University from January 2023 to December 2023 were selected as the research subjects.Patients were divided into a sleep disorder group(n=44)and a non-sleep disorder group(n=66)based on the Athens insomnia scale(AIS)score.Baseline data and laboratory indicators were compared between the two groups;Binary logistic regression was used to analyze the influencing factors of sleep disorders in lung cancer chemotherapy patients,build a decision tree model,and draw receiver operating characteristic curves(ROC)to verify the predictive efficiency of the decision tree model.Results The incidence of sleep disorders in lung cancer chemotherapy patients[40.00％(44/110)];The chemotherapy cycle,visual analog scale(VAS)score,inter-leukin-6(IL-6),tumor necrosis factor-α(TNF-α),and C-reactive protein(CRP)in the sleep disorder group were higher than those in the non-sleep disorder group.The proportion of stage Ⅲ-Ⅳ and the use of paclitaxel+platinum chemotherapy regimen was higher in the sleep disorder group than in the non-sleep disorder group(P＜0.05);According to binary logistic regression analysis,stages Ⅲ-Ⅳ,paclitaxel+platinum chemotherapy regimen,chemotherapy cycle,VAS score,and IL-6 were the influencing factors of sleep disorders in lung cancer chemotherapy patients(OR＞1,P＜0.05).A decision tree model was generated by incorporating these factors,and three explanatory variables including VAS score,IL-6,and TNM staging were screened out.VAS score was the most important root node variable and predic-tor.The AUC of the decision tree prediction model was 0.915,P＜0.001,indicating a high predictive value.Conclu-sion The decision tree model constructed by TNM staging,chemotherapy regimen,chemotherapy cycle,VAS score,and IL-6 has a high predictive value for sleep disorders in lung cancer chemotherapy patients.
Lung cancerSleep disordersChemotherapyInfluencing factorsDecision tree
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