Pd-catalyzed Suzuki-Miyaura coupling reaction is the most direct and effective method to construct C-C bonds,which is of great significance in the preparation of biaryl natural products,phar-maceutical intermediates and functional materials.Introduces the related contents of research frontier hot spots to organic experiment teaching of undergraduate students,through the experiment,students can learn the consulting method of chemical literature,understand the forefront of transition metal ca-talysis research progress,master the methods of TLC monitoring reaction,extraction and column chro-matography purification methods,learning nuclear magnetic resonance(NMR),high performance liq-uid chromatography(HPLC)method for the identification of compound structure.Make the students experience the whole process of organic chemistry scientific research experiment,train the students' practical ability and innovation ability,stimulate the students'interest in scientific research,effectively train the students'innovative thinking and independent analysis of problems,solve problems and other comprehensive ability.
关键词
过渡金属催化/钯催化/Suzuki-Miyaura偶联反应/有机综合实验
Key words
transition metal catalysis/palladium catalyst/Suzuki-Miyaura coupling reaction/organic comprehensive experiment
万方数据