Objective To explore the clinical efficacy of antegrade Kirschner wire intramedullary fixation on the treatment of metatarsal neck fractures.Methods A retrospective analysis was conducted on the clinical data of 23 patients with metatarsal neck fractures admitted from September 2018 to June 2022.All patients underwent antegrade Kirschner wire intramedullary fixation surgery to observe the incidence of postoperative complications and treatment efficacy.Results All 23 patients underwent surgery successfully,with a single metatarsal bone surgery time of(6.91±2.09)minutes and a hospital stay of(4.91±1.08)days.The incision healed in the first stage,and there were no complications such as incision infection,re-displacement of the fracture,or loosening of the Kirschner wire.At least 6 months of follow-up,all patients achieved bone healing.The fracture healing time was 6-12 weeks,with an average healing time of(8.39±2.06)weeks.At the last follow-up,the AOFAS forefoot score was 83-100 points,with an average score of(92.26±5.99)points.Among them,16 cases were excellent,7 cases were good,and the excellent and good rate was 100%.Conclusion Antegrade Kirschner wire intramedullary fixation for the treatment of metatarsal neck fractures has achieved good therapeutic effects,with the advantages of minimally invasive,minimal body damage,low cost,short hospital stay,fast postoperative recovery,no need for secondary hospitalization surgery,and easy acceptance by patients.It is a treatment method worth promoting.