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一起由GⅡ型诺如病毒引起的食源性疾病暴发调查

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目的 调查2021年北京市某学校急性胃肠炎暴发疫情的发生原因和致病因素.方法 通过描述性流行病学方法描述病例的临床表现和三间分布,结合病例对照研究、回顾性队列研究和logistic回归分析查找可疑暴露餐次和可疑暴露食品.开展现场卫生学调查,采集病例标本、食品加工工具及环境涂抹样本进行诺如病毒PCR检测.结果 共搜索到92名病例,临床症状主要为呕吐(84.78%),其次为恶心(58.70%)、腹泻(31.52%)、腹痛(29.35%)和发热(25.00%).现场流行病学调查结果显示,可疑暴露餐次为4月1日早餐,可疑致病食品为果仁黄瓜,感染诺如病毒的厨工在食堂工作期间排毒使其制作的菜品被污染是可能的主要感染环节.在72份粪便/肛拭子样本中检出23株G Ⅱ型诺如病毒株.结论 该次疫情为一起G Ⅱ型诺如病毒引起的学校食源性急性胃肠炎暴发疫情.食用了被诺如病毒污染的果仁黄瓜是导致该次食源性疾病暴发的主要原因.
An outbreak of foodborne illness caused by norovirus GⅡ
Objective To survey the causes and pathogenic factors of an outbreak of acute gastroenteritis occurred in a school in Beijing in 2021.Methods The clinical manifestations of the cases and their time,regional and population distribution were described with descriptive epidemiological methods.Case-control study,retrospective cohort study and logistic regression analysis were used to find out the suspected exposed meals and suspected pathogenic food.A field hygienic survey was carried out.Samples from the cases,food processing tools and environment were collected for the PCR detection of norovirus.Results A total of 92 cases were detected,and their main clinical symptom was vomiting(84.78%),followed by nausea(58.70%),diarrhea(31.52%),abdominal pain(29.35%)and fever(25.00%).The results of the field epidemiological survey demonstrated that the breakfast on April 1st was the suspected exposed meal,and kernel cucumber was the suspected pathogenic food,which might be contaminated by a kitchen worker with norovirus infection during the preparation in the canteen.23 strains of norovirus GⅡ were detected from 72 stool samples/anal swabs.Conclusion This is an outbreak of foodborne acute gastroenteritis caused by norovirus GⅡ in the school.The kernel cucumber contaminated by norovirus is the main infection source of this outbreak of foodborne illness.

norovirusfoodborne illnessacute gastroenteritisinvestigation and analysisoutbreak

徐得月、王明良、王玮、白云、任丽君、白晓潇、刘聪伟、苏领彦

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北京市石景山区疾病预防控制中心,北京 100043

诺如病毒 食源性疾病 急性胃肠炎 调查分析 暴发

北京市重大疫情防治重点专科项目

京卫医[2021]135号

2024

实用预防医学
中华预防医学会 湖南省预防医学会

实用预防医学

CSTPCD
影响因子:1.391
ISSN:1006-3110
年,卷(期):2024.31(1)
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