Epidemic characteristics of acute flaccid paralysis cases in Hefei City,2012-2020
Objective To investigate the epidemic features of acute flaccid paralysis(AFP)cases in Hefei City during 2012-2020,and to provide a basis for developing strategies for consolidating the polio-free situation.Methods The epidemiological data about AFP cases in Hefei City from 2012 to 2020 were collected,and then statistically analyzed by descriptive epidemiological method.Spatial autocorrelation analysis was performed using R 4.3.0.Results A total of 246 AFP cases were cumulatively reported in Hefei City from 2012 to 2020,with the average annual reported incidence rate being 2.14/100,000.The differences in the seasonality of the incidence were not obvious.The proportion of male to female was 2.15∶1.The incidence rate of the group aged 2 years was the highest(8.41/100,000),while the incidence rate of the group aged 8 years was the lowest(0.78/100,000).96.75％of the cases had completed at least three primary doses of polio vaccine,and 86.21％of the cases in the group aged 4-15 years had completed the fourth dose of polio vaccine.The follow-up visit at the 60th day after paralysis showed that 10.98％cases still had residual paralysis.99.59％of the cases were followed up by CDC staff.Spatial autocorrelation analysis displayed that the high-high cluster area of the reported incidence in 2020 was located in Baohe District,while the low-low cluster area was located in Lujiang County.Conclusion It is necessary to improve the grass-roots clinicians'ability in early differentiation and diagnosis of AFP cases in Hefei City,promote booster immunization of polio vaccine,pay more attention to residual paralysis sequelae,encourage rehabilitation doctors to participate in follow-up visits,and explore targeted regional prevention and control strategies.
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