首页|湖南省6~15岁中小学生血清25(OH)D水平及与视力不良关联性研究

湖南省6~15岁中小学生血清25(OH)D水平及与视力不良关联性研究

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目的 分析湖南省6~15岁中小学生血清25(OH)D水平以及维生素D缺乏的流行病学分布特征,并探讨中小学生血清25(OH)D水平与视力不良的关联性.方法 2021年选取6个监测县6~15岁的小学生和初中生,对其血清25(OH)D浓度、视力、身高、体重进行检测,收集白天户外活动时长、每天电子产品使用时间等信息.结果 调查的1 987名6~15岁中小学生,血清25(OH)D平均含量为19.49 ng/ml,其中男生平均含量为20.57 ng/ml,女生平均含量为18.38 ng/ml,男生高于女生(P<0.001);血清25(OH)D含量水平随着年龄增加呈下降趋势(P<0.001);仅46.7%的学生血清25(OH)D含量充足;肥胖学生血清25(OH)D平均含量明显低于其他营养水平的学生(P<0.05);白天户外活动不足1 h的学生血清25(OH)D平均含量明显低于可活动1 h以上的学生(P<0.001);随着学龄段的上升,学生白天户外活动时长呈减少趋势(P<0.001);视力不良者达49.8%,随着学龄段的升高,视力不良程度呈加重趋势(P<0.001).白天户外活动时长不足2 h的学生,随着维生素D缺少程度的加重,视力不良发生率亦会增加(P<0.001).结论 血清25(OH)D水平与年龄、性别、学校所在地、营养状况、白天户外活动时长等因素有关,血清25(OH)D水平充足与否与视力不良存在一定的关联.
Serum 25(OH)D level and its correlation with poor eyesight in primary and secondary school students aged 6-15 years in Hunan Province
Objective To analyze the serum 25(OH)D level and the epidemiological distribution characteristics of vitamin D deficiency among primary and secondary school students aged 6-15 years in Hunan Province,and to explore the correlation between serum 25(OH)D level and poor eyesight among them.Methods Primary and junior middle school students aged 6-15 years in 6 monitored counties in 2021 were selected to test their serum 25(OH)D concentration,vision,height and weight,and collect the information like time spent outdoors during the daytime and time spent using electronic products per day.Results The average serum 25(OH)D content of 1,987 primary and secondary school students aged 6-15 years was 19.49 ng/ml,and the average serum 25(OH)D content was higher in male students than in female ones(20.57 ng/ml vs.18.38 ng/ml,P<0.001).Serum 25(OH)D content decreased with age increasing(P<0.001).Only 46.7%of the students had sufficient serum 25(OH)D.The average content of serum 25(OH)D was significantly lower in obese students than in students with other nutritional levels(P<0.05),as well as significantly lower in students who spent less than 1 hour for outdoor activities during the daytime than in students who spent more than 1 hour for outdoor activities during the daytime(P<0.001).With the increase of school age,the du-ration of outdoor activities during the daytime showed a decreasing trend(P<0.001).The number of poor visual acuity was 49.8%,and the degree of poor visual acuity increased with the increase of school age(P<0.001).The incidence rate of poor visual acuity in students who spent less than 2 hours for outdoor activities during the daytime also increased with the aggravated degree of vitamin D deficiency.Conclusion Serum 25(OH)D level is related to the factors like age,gender,school location,nutritional status,and duration of daytime outdoor activity,and the inadequate serum 25(OH)D level is associated with poor eyesight.

serum 25(OH)Dpoor eyesightprimary and junior middle school studentsepidemiologycorrelation analysis

胡冀、陈艳华、李开宇、王非、谭雅卿、付中喜

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湖南省疾病预防控制中心,湖南 长沙 410153

血清25(OH)D 视力不良 中小学生 流行病学 相关性分析

2024

实用预防医学
中华预防医学会 湖南省预防医学会

实用预防医学

CSTPCD
影响因子:1.391
ISSN:1006-3110
年,卷(期):2024.31(5)
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