Effectiveness of influenza vaccination among primary and secondary school students in Longgang District of Shenzhen City,2022
Objective To explore and evaluate the protective effect of trivalent inactivated influenza vaccine in primary and secondary school students,and to provide a basis for the government to formulate and improve influenza vaccination strategies for the students.Methods Combined with the number of influenza incidence from the National Monitoring System for Infectious Disease,the number of influenza vaccination in the primary and secondary schools in 2022 and the number of students in each grade,we compared the incidence rates of influenza in each grade and the incidence rates of influenza in the vaccinated and non-vaccinated groups,and calculated the vaccine protection rate of each group.Results The incidence rate of influenza was significantly lower in the vaccinated group than in the non-vaccinated group(4.54％vs.6.02％,x2=251.761,P＜0.05).The overall protection rate offered by influenza vaccines in the primary and secondary schools was 24.55％.The primary and secondary schools were grouped according to the vaccination rates from high to low,the incidence rate of influenza in the low vaccination rate group of primary schools was 6.12％,and the vaccine protection rate-12.31％,with 95％confidence interval of-22.51％--3.02％,showing no protective effect.Other groups showed good protective effects after influenza vaccination.Conclusion Seasonal flu vaccination can effectively protect the primary and middle school students,and hence it is necessary to encourage the primary and middle school students to inoculate with seasonal flu vaccines in accordance with the technical guidelines for flu vaccination so as to prevent influenza.This study supports the current recommendation on inoculating with 2 doses of influenza vaccine in previously unvaccinated children.Multiple measures should be taken in parallel in newly-registered pupils from Grade 1 so as to protect their health.
influenza vaccineprotection effectprimary and secondary school students
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