Objective To analyze the relationship between cardiac ultrasound and major adverse cardiovascular events(MACE)after percutaneous coronary intervention(PCI)in ischemic cardiomyopathy(ICM).Methods Eighty patients with ICM who received PCI treatment in our hospital from October 2020 to October 2022 were selected and divided into two groups according to whether MACE occurred one year after surgery.Eighteen patients with MACE were set as the observation group and 62 patients without MACE were set as the control group.Cardiac ultrasound indexes of the two groups were compared.The risk factors of MACE after PCI in ICM patients were analyzed by univariate and multivariate logistic regression,and the predictive efficacy of cardiac ultrasound for MACE after PCI in ICM patients was analyzed by receiver operating curve(ROC).Results Left ventricular ejection fraction(LVEF)and mitral valve flow spectrum peak E/A(E/A)in observation group were lower than those in control group(P<0.05),and left ventricular end-diastolic diameter(LVEDD)in observation group was higher than that in control group(P<0.05).Age,diabetes,relapse after PCI and C-reactive protein(CRP)were the risk factors for MACE after PCI in ICM patients(P<0.05).The combined detection of LVEF,LVEDD,and E/A predicted the area under the curve(AUC)of MACE in ICM patients after PCI was 0.851,and the 95%CI confidence interval was(0.828,0.958).The prediction sensitivity of LVEF,LVEDD and E/A combined detection(94.1%)was higher than that of single detection(73.5%,69.8%,78.9%)(P<0.05).The specificity of LVEF,LVEDD and E/A combined detection(84.1%)was compared with that of single detection(79.2%,76.0%,80.1%)(P>0.05).Conclusion The occurrence of MACE in ICM patients after PCI is related to many factors,and the combined detection of LVEF,LVEDD and E/A can improve the prediction efficiency of MACE,which has important reference value.