摘要
目的 分析128排CT灌注成像对胃癌患者术后复发预测中的临床价值.方法 选定本院2021年6月至2023年7月就诊的90例胃癌手术患者设为胃癌组,另选取同期本院体检中心90名健康体检者设为健康组,均给予128排CT灌注成像检查.比较2组CT灌注成像参数,比较胃癌患者手术前后CT灌注成像参数.对胃癌患者进行为期3年的随访,比较复发组、未复发组CT灌注成像参数,绘制受试者工作特征曲线(ROC),分析CT灌注成像参数对胃癌术后复发的预测效能.结果 胃癌组表面通透性(PS)、平均通过时间(MTT)、血流量(BF)、血容量(BV)均高于健康组(P＜0.05),胃癌组达峰时间(TTP)低于健康组(P＜0.05).术后 PS、MTT、BV、BF 均低于术前(P＜0.05),术后 TTP 高于术前(P＜0.05).复发组 PS、MTT、BV、BF 均高于未复发组(P＜0.05),复发组TTP低于未复发组(P＜0.05)o PS、MTT、BV、BF、TTP联合检测灵敏度(95.7％)高于单一检测(75.9％、70.3％、68.3％、73.6％、74.3％)(P＜0.05);联合检测特异度(83.8％)与单一检测(81.3％、79.1％、76.8％、82.1％、77.1％)比较差异无统计学意义(P＞0.05).结论 胃癌术后复发128排CT灌注成像参数PS、MTT、BV、BF较高,TTP较低,PS、MTT、BV、BF、TTP联合可提高对胃癌术后复发的预测灵敏度,具有重要参考价值.
Abstract
Objective To analyze the clinical value of 128-slice CT perfusion imaging in predicting postoperative recurrence in patients with gastric cancer.Methods A total of 90 patients undergoing surgery for gastric cancer treated in our hospital from June 2021 to July 2023 were selected as the gastric cancer group,and another 90 healthy patients undergoing physical examination in our hospital during the same period were selected as the healthy group,all of which were given 128-slice CT perfusion imaging examination.CT perfusion imaging parameters of the two groups were compared,and CT perfusion imaging parameters of patients with gastric cancer before and after surgery were compared.The patients with gastric cancer were followed up for 3 years,and the parameters of CT perfusion imaging were compared between the recurrence group and the non-recurrence group,and receiver operating curve(ROC)was drawn to analyze the predictive efficacy of CT perfusion imaging parameters on postoperative recurrence of gastric cancer.Results The surface permeability(PS),mean transit time(MTT),blood flow(BF)and blood volume(BV)of gastric cancer group were higher than those of healthy group(P＜0.05),and the peak time(TTP)of gastric cancer group was lower than that of healthy group(P＜0.05).PS,MTT,BV and BF after operation were lower than before operation(P＜0.05),and TTP after operation was higher than before operation(P＜0.05).PS,MTT,BV and BF in relapsing group were higher than those in non-relapsing group(P＜0.05),and TTP in relapsing group was lower than that in non-relapsing group(P＜0.05).The sensitivity of PS,MTT,BV,BF and TTP combined detection(95.7％)was higher than that of single detection(75.9％,70.3％,68.3％,73.6％,74.3％)(P＜0.05).The specificity of combined detection(83.8％)was compared with that of single detection(81.3％,79.1％,76.8％,82.1％,77.1％)(P＞0.05).Conclusion The 128-slice CT perfusion imaging parameters PS,MTT,BV and BF are higher and TTP is lower.The combination of PS,MTT,BV,BF and TTP can improve the sensitivity of predicting postoperative recurrence of gastric cancer,which has important reference value.
维普
万方数据