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光学相干断层扫描在视网膜中央动脉阻塞的应用

Application of optical coherence tomography in central retinal artery occlusion

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目的 研究应用光学相干断层扫描(OCT)和眼底彩照对视网膜动脉阻塞黄斑区变化图的分析.方法 应用海德堡激光眼科诊断仪(HRA-OCT)对30例视网膜中央动脉阻塞(CRAO)进行OCT检查和眼底彩照,观察其形态学特征.利用OCT图像分析CRAO的特点.用HRA-OCT对19例CRAD患者进行黄斑部水平径线、垂直径线扫描,并眼底照相机眼底照相.13例测量患眼与对侧眼的视网膜中心凹旁鼻,颞侧厚度,SPSS21.0统计软件包,采用配对样本t检验.结果 OCT特征:阻塞的视网膜增厚,内层结构分辨不清,神经上皮层部分反光增强,视网膜内层高反射率高.彩照显示后极部视网膜呈乳白色水肿,黄斑区有樱桃红点.比较患眼与健康眼的视网膜中心凹旁鼻侧厚度(t=-80.992,P<0.001);患眼与健康眼的视网膜中心凹旁颞侧厚度(t=-56.623,P<0.001),以及患眼视网膜中心凹旁颞侧与鼻侧的厚度(t=-60.463,,P<0.001),差异比较有统计学意义(P<0.001).结论 HRA-OCT能无创地观察CRAO视网膜组织形态学改变,对临床诊治提供指导性意义.
Objective Optical coherence tomography(OCT)and color fundus imaging were employed to analyze macular changes in central retinal artery occlusion(CRAO).Methods Thirty CRAO patients were subject to OCT and color fundus imaging by using Heidelberg retina angiograph+OCT(HRA-OCT)to observe morphological characteristics.Analysis of CRAO using OCT image.Using HRA-OCT,30 patients with CRAO were subject to horizontal and vertical scanning of the macula.Fundus images were also obtained.Temporal and nasal parafoveal retinal thickness were measured in 13 eye of the affected and contralateral eye and SPSS21.0 statistical soft ware,was used with paired t test.Results OCT revealed that the occluded retina was thickened,the inner layer structure was unclear,the reflection of neuroepithelial layer was partially enhanced,and the inner layer of the retina had high reflection.Color fundus imaging showed milky white edema in the posterior pole of retina and cherry-red spots in the macular area.The thickness of nasal parafoveal nasal side was compared between the affected eye and the opposite healthy eye(t=-80.992,P<0.001),the parafoveal temporal thickness of the retina was compared between the affected and the opposite healthy eye(t=-56.623,P<0.001).The thickness of the nasal and temporal parafoveal tempore of retina in affected eyes were compared(t=-60.463,P<0.001).It provided guidance for clinical diagnosis and treatment.HRA-OCT offered more valuable imaging data for clinicians.Conclusion HRA-OCT can non-invasively observe the morphological changes of retinal tissues in CRAO and provide significant guidance significance for clinical diagnosis and treatment.

Tomography,optical coherenceFundus oculiCentral retinal artery occlusion

林少芬、毛羽翔

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中山大学中山眼科中心区庄眼底影像室眼病防治全国重点实验室 广东省眼科视觉科学重点实验室,广州 510060

体层摄影术,光学相干 眼底 视网膜中央动脉阻塞

2024

实用医技杂志
山西医药卫生传媒集团有限责任公司

实用医技杂志

影响因子:0.534
ISSN:1671-5098
年,卷(期):2024.31(4)