Objective Optical coherence tomography(OCT)and color fundus imaging were employed to analyze macular changes in central retinal artery occlusion(CRAO).Methods Thirty CRAO patients were subject to OCT and color fundus imaging by using Heidelberg retina angiograph+OCT(HRA-OCT)to observe morphological characteristics.Analysis of CRAO using OCT image.Using HRA-OCT,30 patients with CRAO were subject to horizontal and vertical scanning of the macula.Fundus images were also obtained.Temporal and nasal parafoveal retinal thickness were measured in 13 eye of the affected and contralateral eye and SPSS21.0 statistical soft ware,was used with paired t test.Results OCT revealed that the occluded retina was thickened,the inner layer structure was unclear,the reflection of neuroepithelial layer was partially enhanced,and the inner layer of the retina had high reflection.Color fundus imaging showed milky white edema in the posterior pole of retina and cherry-red spots in the macular area.The thickness of nasal parafoveal nasal side was compared between the affected eye and the opposite healthy eye(t=-80.992,P<0.001),the parafoveal temporal thickness of the retina was compared between the affected and the opposite healthy eye(t=-56.623,P<0.001).The thickness of the nasal and temporal parafoveal tempore of retina in affected eyes were compared(t=-60.463,P<0.001).It provided guidance for clinical diagnosis and treatment.HRA-OCT offered more valuable imaging data for clinicians.Conclusion HRA-OCT can non-invasively observe the morphological changes of retinal tissues in CRAO and provide significant guidance significance for clinical diagnosis and treatment.