Objective To investigate the risk factors of poor prognosis in patients with hemorrhagic stroke,in order to provide guidance for better clinical treatment.Methods Among the patients with hemorrhagic stroke admitted to the hospital from June 2020 to June 2023,the data of 80 patients eligible for the study were collected based on the inclusion and exclusion criteria for retrospective analysis,and the general data,imaging data,laboratory examination indicators and prognosis assessed by the modified ranking scale(mRS)were collected.Patients were divided into good prognosis group and poor prognosis group according to their prognosis.The general data distribution and laboratory test results of the two groups were compared,and the risk factors for poor prognosis were analyzed by logistic regression.Results The poor prognosis rate of 80 patients with hemorrhagic stroke was 45.0%.Logistic regression analysis,age 60 or more[OR(95%CI)=2.204(1.064,3.849),P=0.016],hypertension[OR(95%CI)=1.815(1.285,2.562),P=0.001],diabetes mellitus[OR(95%CI)=2.266(1.020,5.032),P=0.022],Glasgow coma score(GCS)<91[OR(95%CI)=3.330(2.044,5.425),P=0.000],NIHSS score>15 points[OR(95%CI)=2.219(1.216,4.050),P=0.005],broken into the ventricle[OR(95%CI)=2.349(1.300,4.246),P=0.002],the bleeding ≥ 30 ml[OR(95%CI)=2.160(1.211,3.850),P=0.005],the residual hematoma volume ≥ 15 ml[OR(95%CI)=2.568(1.396,4.724),P=0.005),elevated C-reactive protein(CRP)[OR(95%CI)=2.784(1.424,5.443),P=0.001],white blood cell count(WBC)increased[OR(95%CI)=6.141(1.246,30.279),P=0.013]and the level of glomerular filtration rate(GFR)[OR(95%CI)=2.286(1.010,5.177),P=0.024]were risk factors affecting the prognosis of patients.Conclusion The prognosis of patients with hemorrhagic stroke is mainly related to age,history of combined hypertension or diabetes,GCS and NIHSS scores,presence of ventricle rupture,large volume of blood loss and residual hematoma,inflammation level and GFR level.The prognosis of patients can be predicted based on clinical risk factors,which can provide basis for individual management of patients.