Objective To analyze the clinical value of treponema pallidum antibody test(TP-AB)combined with rapid plasma reagin ring card test(RPR)in serological detection of syphilis.Methods A total of 150 patients with high suspected syphilis who received outpatient treatment in our hospital from January 2021 to December 2022 were selected and given TP-AB and RPR examinations respectively.TPPA was used as the diagnostic gold standard,and the diagnostic accuracy,sensitivity and specificity of TP-AB,RPR and TP-AB+RPR were compared.The results of Kappa consistency test were analyzed.Results One hundred and sixteen cases of TPPA were positive,34 cases were negative.The diagnostic accuracy(97.3％)and sensitivity(99.1％)of TP-AB+RPR were higher than those of TP-AB(90.7％、88.0％)and RPR(91.4％、88.8％)(P＜0.05).The diagnostic specificity of TP-AB+RPR(91.2％)was compared with that of TP-AB(88.2％)and RPR(85.3％)(P＞0.05).The comparison between TP-AB and TPPA was generally consistent,and Kappa value was 0.603.There was no consistency between RPR and TPPA,and the Kappa value was 0.297.TP-AB+RPR was consistent with TPPA,and the Kappa value was 0.933.Conclusion The combination of TP-AB and RPR can improve the diagnostic accuracy and sensitivity of syphilis,and has important reference value.
Syphilis serodiagnosisTreponema pallidum antibody detectionRapid plasma reagin circle card test
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