Objective To analyze the application value of human papillomavirus(HPV)genotyping detection in cervical lesions.Methods The clinical data of 3 760 women who underwent cervical lesion screening and were HPV positive from January 2021 to December 2023 were retrospectively analyzed.All the women underwent HPV genotyping and liquid based cytology test(TCT).As a pathological examination,cervical biopsy pathology was taken as the gold standard,68 cases were confirmed to have cervical lesions(CIN Ⅰ～Ⅲ:65 cases;canceration:3 cases).The positive rate of HPV,HPV genotyping distribution,high risk HPV and TCT examination in patients with different cervical lesions were analyzed.Results HPV single infection accounted for 73.99％(2 782/3 760),high-risk infection accounted for 73.94％(2 780/3 760),low-risk infection accounted for 0.05％(2/3 760).HPV 52+other subtypes,HPV 53+other subtypes and HPV-58+other subtypes were the main types of HPV multiple infection.The detection rate of HPV genotyping for cervical lesions was higher than that of TCT,and the difference was statistically significant(P＜0.05).Conclusion HPV genotyping test is helpful to understand the HPV infection situation of patients,and has high clinical auxiliary examination value for cervical lesions.
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万方数据
