Objective To investigate the therapeutic effect of pure titanium stent and cobalt-chromium stent prosthesis in the treatment of mild to moderate periodontal disease with dentition defect and the influence on the levels of C-reactive protein(CRP),tumor necrosis factor α(TNF-α)and interleukin-6(IL-6)in gingival crevicular fluid.Methods From January 2021 to December 2022,120 patients with mild to moderate periodontal disease with dentition defect in our hospital were selected and divided into cobalt-chromium alloy group and pure titanium group according to dentures of different metal types.Forty cases in the cobalt-chromium alloy group were treated with removable dentures with cobalt-chromium stent,and 40 cases in the pure titanium group were treated with removable dentures with pure titanium stent,and were followed up for 1 year.The clinical efficacy,masticatory efficiency and the occurrence of adverse symptoms during follow-up were observed.In addition,a blank control group of 40 cases was added,and the control group was treated with movable denture without metal resin material,and the inflammation level of gingival crevicular fluid was compared among the three groups.Results The total effective rate was significantly different between the two groups(P＞0.05).The masticatory efficiency of both groups after 6 months of repair was higher than that before repair,and that of pure titanium group was higher than that of cobalt-chromium alloy group(P＜0.05).The levels of CRP.TNF-α and IL-6 in gingival crevicular 1 fluid of three groups after 1 month of repair were lower than those before repair,and cobalt-chromium alloy group had better results than the pure titanium group,which in turn had better results than the control group,with significant difference(P＜0.05).The incidence of adverse symptoms in pure titanium group was significantly lower than that in cobalt chromium group(P＜0.05).Conclusion Pure titanium stent and cobalt-chromium alloy stent removable denture repair are both effective means for clinical treatment of mild to moderate periodontal disease with dentition defect.Although both metal stents will inevitably lead to certain gingival crevicular fluid inflammation,pure titanium stent is more beneficial to improve chewing effect,relieve gingival crevicular fluid inflammation,and prevent various adverse symptoms.
关键词
纯钛支架/钴铬合金支架/义齿/牙周病/牙列缺损/疗效
Key words
Pure titanium stent/Cobalt-chromium alloy bracket/Denture/Periodontal disease/Dentition defect/Curative effect
万方数据