首页|0~14岁儿童尿路感染69例病原菌构成和临床特点分析

0~14岁儿童尿路感染69例病原菌构成和临床特点分析

Analysis of pathogen composition and clinical characteristics of urinary tract infections in 69 children aged 0-14 years old

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目的 了解本院69例儿童尿路感染的主要病原菌构成及临床特点.方法 选择2020年3月至2024年2月于泉州市第一医院就诊,中段尿培养阳性并临床明确诊断为尿路感染的0~14岁儿童69例作为研究对象.回顾性收集患儿的临床资料和中段尿培养阳性结果,统计病原菌株的主要构成.根据患儿的年龄,分为婴儿组(<1岁)、幼儿组(1~3岁)、学龄前组(4~7岁)、学龄组(8~14岁).比较不同组患儿临床特点是否存在差异.结果 69例患儿阳性标本中革兰阴性菌51例(73.9%)、革兰阳性菌13例(18.8%).分离病原菌数量前3为大肠埃希菌(50.7%)、粪肠球菌(14.5%)和肺炎克雷伯菌肺炎亚种(11.6%).幼儿组女童占比明显低于其他3组(P=0.016);婴儿组、幼儿组患儿和学龄前组、学龄组患儿在临床表现占比上差异具有统计学意义(P<0.001);4组在影像学异常占比上差异无统计学意义(P=0.194).影像学异常的患儿病原菌分布以非大肠埃希菌为主.结论 大肠埃希菌是本地区儿童尿路感染的主要病原菌.3岁以下儿童临床表现以发热为主,但3岁以上儿童尿路刺激征占比增多.存在影像学异常的患儿应考虑非大肠埃希菌感染,以在患儿早期尿路感染时进行合理的经验用药.
Objective To understand the main pathogen composition and clinical characteristics of 69 children with urinary tract infections(UTI)in our hospital.Methods Sixty-nine children aged 0-14 old with positive midstream urine culture and clinically confirmed diagnosis of UTI at Quanzhou First Hospital from March 2020 to February 2024 were selected as the study subjects.We retrospectively collected the clinical data,midstream urine culture results of pediatric patients,and statistical analysis of the main composition of pathogenic strains was performed.According to the age of the children,they are divided into infant group(<1 year old),child group(1-3 years old),preschool group(4-7 years old),and school-age group(8-14 years old).Differences in clinical characteristics among different groups of children were compared.Results Among the 69 positive specimens of pediatric patients,there were 51 cases of Gram negative bacteria(73.9%),13 cases of Gram positive bacteria(18.8%).The top three pathogens isolated were Escherichia coli(50.7%),Enterococcus faecalis(14.5%),and Klebsiella pneumoniae subspecies pneumonia(11.6%).The proportion of girls in the child group was significantly lower than the other three groups(P=0.016).The difference in the proportion of clinical manifestations between the infant group,the child group,and the preschool and school-age groups was statistically significant(P<0.001).There was no statistically significant difference in the proportion of imaging abnormalities among the four groups(P=0.194).The pathogen distribution in children with imaging abnormalities is mainly non Escherichia coli.Conclusion Escherichia coli is the main pathogen of UTI in children in this region.The clinical manifestations of children under 3 years old are mainly fever,but the proportion of children over 3 years old with urinary tract irritation sign is increasing.Children with imaging abnormalities should consider the direction of non Escherichia coli infection,and receive reasonable empirical medication for early UTI.

ChildUrinary tract infectionsPathogenic bacteriaClinical characteristics

汪文煌、陈清清、王婉妮、彭芃芃、陈雅斌

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福建医科大学附属泉州第一医院检验科,泉州 362000

儿童 泌尿道感染 病原菌 临床特点

2024

实用医技杂志
山西医药卫生传媒集团有限责任公司

实用医技杂志

影响因子:0.534
ISSN:1671-5098
年,卷(期):2024.31(8)