Objective To understand the main pathogen composition and clinical characteristics of 69 children with urinary tract infections(UTI)in our hospital.Methods Sixty-nine children aged 0-14 old with positive midstream urine culture and clinically confirmed diagnosis of UTI at Quanzhou First Hospital from March 2020 to February 2024 were selected as the study subjects.We retrospectively collected the clinical data,midstream urine culture results of pediatric patients,and statistical analysis of the main composition of pathogenic strains was performed.According to the age of the children,they are divided into infant group(<1 year old),child group(1-3 years old),preschool group(4-7 years old),and school-age group(8-14 years old).Differences in clinical characteristics among different groups of children were compared.Results Among the 69 positive specimens of pediatric patients,there were 51 cases of Gram negative bacteria(73.9%),13 cases of Gram positive bacteria(18.8%).The top three pathogens isolated were Escherichia coli(50.7%),Enterococcus faecalis(14.5%),and Klebsiella pneumoniae subspecies pneumonia(11.6%).The proportion of girls in the child group was significantly lower than the other three groups(P=0.016).The difference in the proportion of clinical manifestations between the infant group,the child group,and the preschool and school-age groups was statistically significant(P<0.001).There was no statistically significant difference in the proportion of imaging abnormalities among the four groups(P=0.194).The pathogen distribution in children with imaging abnormalities is mainly non Escherichia coli.Conclusion Escherichia coli is the main pathogen of UTI in children in this region.The clinical manifestations of children under 3 years old are mainly fever,but the proportion of children over 3 years old with urinary tract irritation sign is increasing.Children with imaging abnormalities should consider the direction of non Escherichia coli infection,and receive reasonable empirical medication for early UTI.