The value of abdominal contrast-enhanced CT combined with serum tumor markers in the diagnosis and prognosis evaluation of primary hepatocellular carcinoma
The value of abdominal contrast-enhanced CT combined with serum tumor markers in the diagnosis and prognosis evaluation of primary hepatocellular carcinoma
Objective To explore and analysis the values of abdominal contrast-enhanced CT combined with serum tumor markers in the diagnosis and prognosis evaluation of primary hepatocellular carcinoma.Methods From January 2019 to March 2022,42 cases of patients with liver cancer(hepatocellular carcinoma group)and 48 patients with benign liver tumors(benign group)in our hospital were selected as the research subjects.All patients were given abdominal enhanced CT combined with serum tumor markers biochemical detection.Followed-up of patient prognosis and analyzed the predictive value in the hepatocellular carcinoma group.Results The serum AFP content in the hepatocellular carcinoma group were significantly higher than that in the benign group(P＜0.05).The values of HAF,HPI,and HPF in the hepatocellular carcinoma group were significantly higher than those in the benign group(P＜0.05).There were no significant difference in PVP compared between the two groups(P＞0.05).In the two groups of 90 patients,Spearsman analysis showed that AFP,HAF,HPF and HPI were all positively correlated with the occurrence of liver cancer(P＜0.05).All patients in the hepatocellular carcinoma group were followed up until August 1,2022,with an average follow-up time of(21.0±2.2)months,there were 28 patients were survived,14 patients were died,and the mortality rate were 33.3％.The ROC curve showed that the area under the curve of abdominal contrast-enhanced CT combined with serum tumor markers on the prognosis and death of liver cancer were 0.789,95％confidence interval(0.778,0.843)(P＜0.001).Conclusion The patients with liver cancer are often accompanied by abnormal abdominal contrast-enhanced CT parameters and high expression of serum AFP.Abdominal enhanced CT combined with serum tumor markers can assist in the diagnosis of liver cancer,The combination of the two also have good predictive value for the prognosis of liver cancer.
维普
万方数据