The clinical value of anisotropic fraction and apparent diffusion coefficient values in the diagnosis of brain metastases using 3.0T magnetic resonance diffusion tensor imaging
Objective To analyze the clinical value of anisotropic fraction(FA)and apparent diffusion coefficient(ADC)values in the diagnosis of brain metastases(BM)using 3.OT magnetic resonance diffusion tensor imaging(DTI).Methods A total of 120 BM patients who visited our hospital from January 2020 to April 2024 were selected as the observation group,and 70 high-grade gliomas(HGG)patients who visited our hospital during the same period were selected as the control group.DTI examination was performed on both groups to compare the FA and ADC values of solid tumor areas and peritumoral edema areas,and to compare the DTI imaging characteristics of the two groups.Receiver operating characteristic(ROC)curves were drawn to analyze the diagnostic efficacy of FA and ADC values for BM.Results There was no significant difference in FA value(0.13±0.05)and ADC value(1.13±0.25)×10-3mm2/s between the observation group and the control group(0.14±0.05)and(1.12±0.27)×10-3 mm2/s(P＞0.05).The FA value(0.23±0.06)and ADC value(1.52±0.26)×10-3mm2/s in the peritumoral edema area of the observation group were higher than those of the control group(0.14±0.07)and(1.25±0.14)×10-3mm2/s(P＜0.05).There was no significant difference in tumor location between the observation group and the control group(P＞0.05).Comparison of intratumoral bleeding,regular morphology,necrotic cystic changes,enhancement mode,and peritumoral edema between the observation group and the control group(P＜0.05).The area under the curve(AUC)for the combined diagnosis of BM by FA and ADC values is 0.876,with a 95％confidence interval of 0.841-0.947.The sensitivity of the combined diagnosis of BM by FA and ADC values(93.02％)is higher than that of single detection(72.04％,75.96％)(P＜0.05),and the specificity of the combined detection(82.13％)is compared with that of single detection(81.96％,80.04％)(P＞0.05).Conclusion DTI can improve the diagnostic sensitivity of BM by quantitatively detecting FA and ADC values,and has high clinical value in distinguishing BM and HGG.
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