Objective To study the correlation between cervical precancerous lesions and human papilloma virus(HPV)infection and squamous cell antigen(SCC).Methods A total of patients with cervical lesions admitted to our hospital and 75 patients with cervicitis treated in our hospital(control group)from April 2023 to January 2024 were selected as research objects.Relevant data of 120 patients with cervical lesions were analyzed,and they were divided into cervical cancer group(45 cases)and precancerous lesion group(75 cases)according to different conditions.HPV detection and SCC detection were performed on all participants.HPV positive rate,HPV viral load,SCC positive rate and SCC level in the three groups were compared.pearson correlation test was used to analyze the relationship between cervical precancerous lesions,HPV infection and SCC.Results The positive rate of HPV in cervical cancer group was 93.3％higher than that in precancer group 88.0％and control group 20.0％,and the precancer group was higher than that in control group again(P＜0.05),and HPV viral load in cervical cancer group was significantly higher than that in precancer group and control group(P＜0.05).The SCC positive rate of cervical cancer group was 91.1％higher than that of precancer group 80.0％and control group 26.8％,and the precancer group was higher than the control group(P＜0.05),and the SCC level of cervical cancer group was higher than that of precancer group and control group(P＜0.05).By Pearson analysis,HPV infection was significantly correlated with cervical precancerous lesions(P＜0.05).According to Pearson analysis,SCC was positively correlated with precancerous lesions(P＜0.05).Conclusion The positive rate of HPV and SCC in patients with cervical precancer was analyzed,and it was found that the higher the positive rate was,the more serious the precancer was,which could be used as a relevant factor to evaluate cervical precancer and guide clinical treatment.
万方数据
维普
