Objective To observe the therapeutic effect of different minimally invasive soft channel puncture and drainage on patients with cerebral hemorrhage.Methods A retrospective selection was conducted on 117 patients with cerebral hemorrhage admitted to Nanyang Central Hospital from October 2022 to October 2023.According to different treatment methods,they were divided into control group(n=56)who received traditional minimally invasive soft channel puncture and drainage surgery,and experimental group(n=61)who received minimally invasive soft channel puncture and drainage surgery guided by CT three-dimensional reconstruction.Surgical related indicators(surgical time,one-time success rate of intubation,12 h intracerebral hematoma clearance rate,postoperative hospital stay),serum brain-derived neurotrophic factor(BDNF)and aquaporin-4(AQP4)levels,degree of neurological deficits,and incidence of postoperative complications were compared.Results There was no significant difference in the clearance rate of intracerebral hematoma between the two groups(P＞0.05),but the one-time success rate of intubation in experimental group was significantly higher than that in control group,the surgical time and postoperative hospital stay were significantly shorter than those in control group(P＜0.05);14 days after surgery,the serum BDNF level in experimental group was significantly higher than that in control group,and the serum AQP4 level was significantly lower than that in control group(P＜0.05);Six months after surgery,the National Institutes of Health Stroke Scale(NIHSS)score in experimental group was significantly lower than that in control group(P＜0.05);The total incidence of postoperative complications in experimental group was significantly lower than that in control group(P＜0.05).Conclusion CT three-dimensional reconstruction guided minimally invasive soft channel puncture and drainage for the treatment of cerebral hemorrhage has a hematoma clearance rate comparable to conventional minimally invasive puncture and drainage,and it can effectively shorten surgical time,hospital stay,improve intubation success rate,cause minimal damage to neurological function,and effectively regulate serum BDNF AQP4 level,have less postoperative complications,be safe and reliable.
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