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子宫内膜透明细胞癌的临床和超声特征

Clinical and ultrasonographic features of endometrial clear cell carcinoma

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目的 探讨并总结子宫内膜透明细胞癌(ECCC)的临床表现和超声特征.方法 回顾性分析我院2015年1月至2024年1月经手术病理证实的10例ECCC患者的临床资料及超声声像图,分析总结其临床及超声特征.结果 10例ECCC的发病平均年龄(65.2±2.3)岁,病灶平均最大径(6.5±1.0)cm.因触及腹部包块就诊4例(40%),阴道不规则出血就诊6例(60%).8例糖类抗原125(CA125)均正常,2例CA125轻度增高.10例ECCC中6例(60%)呈单房囊实性回声,4例(40%)呈实性均匀中等回声;4例(40%)形态规则,6例(60%)形态不规则;4例(40%)与肌层分界清晰,6例(60%)与肌层分界不清.彩色多普勒显示8例(80%)少量血流信号,阻力指数(RI)均<0.4,2例(20%)未见血流信号.国际妇产科联盟分期:Ⅰ期4例,2例局限于子宫内膜,2例侵犯子宫浅肌层;Ⅱ期4例,病灶侵犯宫颈间质部;Ⅲ期2例,出现盆腔淋巴结转移.结论 ECCG好发于老年女性,超声表现具有一定特征性,囊实性肿块中实性成分形态不规则,呈均匀中等回声,囊性成分充满密集点状回声呈毛玻璃样;实性肿块形态欠规则,呈均匀中等回声.结合临床病史可提高术前诊断率.
Objective To explore and summarize the clinical manifestations and ultrasound features of endometrial clear cell carcinoma.Methods A retrospective analysis was conducted on the clinical data and ultrasound images of 5 patients with endometrial clear cell carcinoma confirmed by surgical pathology in our hospital from January 2015 to January 2024.The clinical and ultrasound characteristics were analyzed and summarized.Results The average age of onset for the 10 cases of ECCC was(65.2±2.3)years old.The average maximum diameter of the lesion is(6.5±1.0)cm.Four cases(40%)were treated for palpation of abdominal masses,and six cases(60%)were treated for irregular vaginal bleeding.Eight cases of CA125 were all normal,while two case had mild elevation of CA125.Among the 10 cases of ECCC,6 cases(60%)showed solid echogenicity in a single chamber cyst,and 4 cases(40%)showed solid,uniform,and moderate echogenicity;4 cases had regular morphology,and 6 cases(60%)had irregular morphology;4 cases(40%)had clear boundaries with the muscular layer,while 6 cases(60%)had unclear boundaries with the muscular layer.Color Doppler showed a small amount of blood flow signal in 8 cases(80%),with resistance index(RI)all less than 0.4,and no blood flow signal in 2 cases(20%).FIGO staging:4 cases in stage Ⅰ,2 cases limited to the endometrium,and 2 cases invaded the superficial layer of the uterus;4 cases of stage Ⅱ,with lesions invading the cervical interstitium;2 cases in stageⅢ showed pelvic lymph node metastasis.Conclusion Endometrial clear cell carcinoma is more common in elderly women,and ultrasound findings have certain characteristics.The solid components in the cystic solid mass are irregular in shape,with uniform and moderate echogenicity.The cystic components are filled with dense punctate echogenicity,with ground glass like appearance;The solid mass has an irregular shape and presents a uniform moderate echogenicity.Combining clinical medical history can improve the preoperative diagnostic rate.

Clinical featuresUltrasonographic featuresEndometrial clear cell carcinoma

姚伟彪、唐琪、朱丽霞

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昆山市第一人民医院超声科,昆山 215300

昆山市第一人民医院妇产科,昆山 215300

临床特征 超声特征 子宫内膜透明细胞癌

2024

实用医技杂志
山西医药卫生传媒集团有限责任公司

实用医技杂志

影响因子:0.534
ISSN:1671-5098
年,卷(期):2024.31(11)