Objective To explore the application value of color Doppler ultrasound parameters of uterine artery and internal iliac artery in predicting adverse pregnancy outcomes during mid pregnancy.Methods Clinical data of 70 pregnant women who underwent prenatal examination and delivery in our hospital from January 2020 to January 2023 were retrospectively collected.According to the pregnancy outcomes of the two groups,they were divided into a good group and an adverse group,with 48 cases in the good group and 22 cases in the adverse group.Compare the blood flow parameters of uterine artery and iliac artery in two groups using color Doppler ultrasound;Analyze the predictive value of color Doppler ultrasound blood flow parameter levels of uterine artery and iliac artery in mid pregnancy for adverse pregnancy outcomes.Results The results showed that the uterine artery pulsatility index(PI),resistance index(RI),peak systolic to diastolic blood flow velocity ratio(S/D),internal iliac artery S/D,and blood flow acceleration time(AT)in the good group were lower than those in the poor group(P<0.05).Logistic multivariate regression analysis showed that elevated uterine artery PI,RI,S/D,and internal iliac artery S/D,AT values were all potential risk factors for adverse pregnancy outcomes(P<0.05);Receiver operating characteristic analysis showed that the sensitivity of PI,RI,S/D of uterine artery and S/D,AT of internal iliac artery in predicting adverse pregnancy outcomes were 86.4%,72.7%,81.8%,63.6%and 77.3%,respectively;The sensitivity of the combination of five parameters in predicting adverse pregnancy outcomes was 90.9%,which was higher than the sensitivity of single parameter prediction(P<0.05).Conclusion Abnormal increases in PI,RI,S/D,and S/D,AT values of the uterine arteries in the second trimester of pregnancy are risk factors for adverse pregnancy outcomes.Combined monitoring of these values can improve the predictive value of adverse pregnancy outcomes.