实用医技杂志2024,Vol.31Issue(12) :864-867.DOI:10.19522/j.cnki.1671-5098.2024.12.007

磁共振成像肝细胞特异性对比剂钆塞酸二钠在肝硬化背景下肝实质内结节中的鉴别应用

Application of magnetic resonance imaging hepatocellular specific contrast agent disodium gadolinate in the identification of intrahepatic parenchymal nodules in the context of liver cirrhosis

王天杰 田启栋 蔡振岩
实用医技杂志2024,Vol.31Issue(12) :864-867.DOI:10.19522/j.cnki.1671-5098.2024.12.007

磁共振成像肝细胞特异性对比剂钆塞酸二钠在肝硬化背景下肝实质内结节中的鉴别应用

Application of magnetic resonance imaging hepatocellular specific contrast agent disodium gadolinate in the identification of intrahepatic parenchymal nodules in the context of liver cirrhosis

王天杰 1田启栋 2蔡振岩3
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作者信息

  • 1. 商丘市中医院核磁共振室,商丘 476000
  • 2. 商丘市第三人民医院影像科,商丘 476000
  • 3. 商丘市第四人民医院放射科,商丘 476000
  • 折叠

摘要

目的 探讨磁共振成像(MRI)肝细胞特异性对比剂钆塞酸二钠(Gd-EOB-DTPA)在肝硬化背景下肝实质内结节中的诊断价值.方法 选择2021年1月至2023年1月我科影像学检查发现的65例(78个结节)肝硬化患者,均接受MRI肝细胞特异性对比剂Gd-EOB-DTPA扫描检查,根据手术或病理检查结果,将结节分为再生结节(RN)、不典型增生(DN)和肝细胞癌(HCC),比较各结节扫面参数,并评价MRI Gd-EOB-DTPA 对肝硬化背景下肝脏结节的诊断价值.结果 本研究入组65例患者78个结节,手术及病理检查检出RN 28个,DN 32例,HCC 18个.HCC组、DN组、RN组ADC值、T,增加率依次升高,T,弛豫时间依次降低(P<0.05).Gd-EOB-DTPA增强MRI扫描与手术及病理检查一致性良好(Kappa值=0.803),且诊断符合率为87.2%(68/78).结论 MRI Gd-EOB-DTPA能够准确鉴别肝硬化背景下的肝实质结节,对肝细胞癌具有较高的诊断效能,适合推广应用.

Abstract

Objective To evaluate the diagnostic value of MRI hepatocellular specific contrast agent disodium gadolinate(Gd-EOB-DTPA)in hepatic parenchymal nodules in the context of liver cirrhosis.Methods Sixty-five patients(78 nodules)with cirrhosis identified by imaging examination in our department from January 2021 to January 2023 were selected,all of whom received MRI hepatocellular specific contrast agent Gd-EOB-DTPA scanning examination.Nodules were divided into RN,DN and HCC according to surgical or pathological examination results,and the scanning parameters of each nodules were compared.To evaluate the diagnostic value of MRI Gd-EOB-DTPA for hepatic nodules in the background of cirrhosis.Results There were 78 nodules in 65 patients enrolled in this study,28 RN,32 DN and 18 HCC were detected by surgical and pathological examination.ADC value and T1 increase rate in HCC group,DN group and RN group were increased successively,and T1 relaxation time was decreased successively(P<0.05).Gd-EOB-DTPA enhanced MRI scan was in good agreement with surgical and pathological examination(Kappa=0.803),and the diagnostic coincidence rate was 87.2%(68/78).Conclusion MRI Gd-EOB-DTPA can accurately identify hepatic parenchymal nodules in the background of cirrhosis,and has high diagnostic efficiency for hepatocellular carcinoma,which is suitable for popularization and application.

关键词

磁共振成像/钆塞酸二钠/肝硬化/肝肿瘤

Key words

Magnetic resonance imaging/Disodium gadolinium/Liver cirrhosis/Liver tumor

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出版年

2024
实用医技杂志
山西医药卫生传媒集团有限责任公司

实用医技杂志

影响因子:0.534
ISSN:1671-5098
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