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卵巢抵抗综合征和早发性卵巢功能不全诊断与个体化管理进展

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卵巢抵抗综合征(ROS)与早发性卵巢功能不全(POI)同属于高促性腺激素性闭经,两者存在相似的临床特点,通常较难鉴别,ROS易被误诊为POI,给后续治疗带来极大挑战.因此,了解ROS和POI的病因、临床特点和诊断标准,尽早明确诊断并制定合理的治疗方案对于有生育要求的患者至关重要.该文系统、全面地探讨了ROS与POI的病因和发病机制、临床特点与诊断以及个体化管理等方面的研究进展,旨在为临床医师提供参考,以便尽早明确诊断,避免误诊误治,并通过个体化管理,帮助患者改善症状并实现生育愿望.
Diagnosis and advances in individualized management of resistant ovary syndrome and premature ovarian insufficiency
Resistant ovary syndrome(ROS)and premature ovarian insufficiency(POI)fall under the cat-egory of hypogonadotropic amenorrhea,sharing similar clinical features that often pose challenges in differentiation.ROS can be easily misdiagnosed as POI,which presents a significant obstacle to subsequent treatment.Therefore,it is crucial for patients with fertility requirements to have a clear understanding of the etiology,clinical features,and diagnostic criteria of ROS and POI in order to establish an early diagnosis and develop an appropriate treatment plan.This article provides a systematic and comprehensive discussion on the research progress regarding the eti-ology and pathogenesis,clinical features and diagnosis,as well as individualized management of ROS and POI.The aim is to offer reference for clinicians in achieving early clarification of diagnoses,avoiding misdiagnosis or mistreatment,while assisting patients in improving symptoms and realizing their fertility aspirations through person-alized management.

resistant ovary syndromepremature ovarian insufficiencydiagnosisindividual man-agement

尚丹丹、刘萍、刘利贞、庞益伟、周超

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滨州医学院附属医院妇科(山东 滨州 256603)

海南西部中心医院生殖医学科(海南 儋州 571799)

滨州医学院附属医院生殖医学科(山东 滨州 256603)

卵巢抵抗综合征 早发性卵巢功能不全 诊断 个体化管理

2025

实用医学杂志
广东省医学情报研究所

实用医学杂志

北大核心
影响因子:1.549
ISSN:1006-5725
年,卷(期):2025.41(1)