Influence of cilioretinal artery on central visual acuity of eyes with non-arteritic central retinal artery occlusion
Objective To observe the influence of the cilioretinal artery on the central visual acuity of the affected eyes at the onset of non-arteritic central retinal artery occlusion(NA-CRAO),and to investigate the prognosis.Methods From September 2011 to March 2023,216 patients(216 eyes)with NA-CRAO underwent fundus fluorescein angiography in Henan Provincial People's Hospital,showing that the fluorescence filling interval between the main trunk and the distal end of the retinal artery was ≥ 5 s,among whom 151 patients(151 eyes)were found no cilioretinal artery(non-cilioretinal artery group),15 patients(15 eyes)were found cilioretinal artery which supplied the macular area(macula group),and 50 patients(50 eyes)were found cilioretinal artery which did not supply the macular area(non-macula group).The gender ratio,age,time from onset to visit,comorbidities(hypertension,diabetes,hypercholesterolemia,coronary artery disease),smoking habits,alcohol consumption,and cerebral infarction were compared among three groups.On admission,optical coherence tomography was performed to measure the central retinal thickness(CRT)of the affected and healthy eyes.All three groups received conservative treatment.The best-corrected visual acuity(BCVA)was measured on admission,and after 1-and 3-month treatment,and the BCVA was converted to logMAR visual acuity.Results(1)There were no significant differences in the age,time from onset to visit,male ratio,and proportions of smoking habits,alcohol consumption,cerebral infarction,and comorbidities(hypertension,diabetes,hypercholesterolemia,coronary artery disease)among three groups(P＞0.05).(2)There was a significant difference in the CRT of the affected eyes among three groups on admission(F=4.558,P=0.012),and no significant difference in the CRT of the healthy eyes(F=0.277,P=0.758).The CRT of the affected eyes was thinner in macula group[(319.87±40.33)μm]than that in non-cilioretinal artery group[(358.94±49.46)μm]and non-macula group[(355.66±44.51)μm](P＜0.05),and showed no significant difference between non-cilioretinal artery group and non-macula group(P＞0.05).(3)There were significant differences in the BCVA(logMAR)among three groups on admission,and after 1-and 3-month treatment(P＜0.05).The BCVAs(logMAR)showed no significant differences after 1-and 3-month treatment compared with those on admission in three groups(P＞0.05).The BCVAs(logMAR)were better in macula group on admission and after 1-and 3-month treatment(1.72±0.99,1.50±0.87,1.40±0.80)than those in non-cilioretinal artery group(2.38±0.81,2.29±0.79,2.25±0.78)and non-macula group(2.51±0.79,2.44±0.82,2.37±0.82)(P＜0.05),and showed no significant difference between non-cilioretinal artery group and non-macula group(P＞0.05).Conclusions Conservative treatment achieves no obvious improvement in the central visual acuity of the NA-CRAO affected eyes.The cilioretinal artery supplying the macular area can protect the central visual acuity of the affected eyes at the onset of NA-CRAO,while the cilioretinal artery supplying no macular area has no protective effect.
central retinal artery occlusioncilioretinal arterycentral visual acuity
NETL
NSTL
万方数据
维普
