首页|男性体质量指数对宫腔内人工授精助孕妊娠结局的影响

男性体质量指数对宫腔内人工授精助孕妊娠结局的影响

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目的 分析行宫腔内人工授精(IUI)助孕夫妇的临床资料,探讨男性体质量指数(BMI)对IUI助孕妊娠结局的影响。方法 2021年6月—2022年6月河南省人民医院行IUI助孕的夫妇306对,根据男性BMI分为肥胖组(≥28。0 kg/m2)82例、超重组(24~<28 kg/m2)131例、正常组(18。5~<24 kg/m2)93例。比较3组女方年龄、BMI、抗米勒管激素、基础窦卵泡计数、手术日子宫内膜厚度,男方年龄、原发不育比率、手术日正常精子率及前向运动精子总数;比较3组妊娠结局(临床妊娠率、活产率、流产率、异位妊娠率)。结果 3组女方年龄、BMI、抗米勒管激素、基础窦卵泡计数、手术 日子宫内膜厚度比较差异均无统计学意义(P>0。05)。肥胖组手术 日前向运动精子总数[30。77(14。19,42。00)×106/mL]均少于超重组[34。30(24。58,50。66)× 106/mL]、正常组[40。25(25。92,66。12)× 106/mL](P<0。05),超重组与正常组比较差异无统计学意义(P>0。05);3组男方年龄、原发不育比率、手术日正常精子率比较差异均无统计学意义(P>0。05)。3组临床妊娠率、异位妊娠率、流产率、活产率比较差异均无统计学意义(P>0。05)。结论 肥胖男性精液前向运动精子总数较超重及正常体质量男性少,但不影响IUI助孕妊娠结局。
Influence of body mass index of the husbands on pregnancy outcomes of intrauterine insemination
Objective To analyze the clinical data of the couples receiving intrauterine insemination(IUI),and to investigate the influence of body mass index(BMI)of the husbands on the pregnancy outcomes.Methods Totally 306 couples receiving IUI in Henan Provincial People's Hospital from June 2021 to June 2022 were divided into obeses group(BMI:≥28.0 kg/m2),overweight group(BMI:24-<28 kg/m2)and normal weight group(BMI:18.5-<24 kg/m2)according to the BMI of the husbands.The clinical data of the wives including age,BMI,anti-Mullerian hormone,basal sinus follicle count and surgery-day endometrial thickness,and the data of the husbands including age,rate of idiopathic infertility,surgery-day normal sperm rate and total progressively motile sperm count were compared among three groups.Results There were no significant differences in the age,BMI,anti-Mullerian hormone,basal sinus follicle count,and surgery-day endometrial thickness of the wives among three groups(P>0.05).The total progressively motile sperm count was less in obese group[30.77(14.19,42.00)X 106/mL]than that in overweight group[34.30(24.58,50.66)X106/mL]and normal weight group[40.25(25.92,66.12)X106/mL](P<0.05),and showed no significant difference between overweight group and normal weight group(P>0.05).There were no significant differences in the age,primary infertility rate,and surgery-day normal sperm rate of the husbands among three groups(P>0.05).There were no significant differences in the rates of clinical pregnancy,ectopic pregnancy,miscarriage,and live birth among three groups(P>0.05).Conclusion The total progressively motile sperm count is less in the obese males than that in overweight males and normal weight males,but obesity does not affect the pregnancy outcome of IUI.

intrauterine inseminationmalesobesitytotal progressively motile sperm countpregnancy outcomes

姜李乐、杨淑珺、张翠莲

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郑州大学人民医院河南省人民医院生殖中心河南省生殖医院,河南郑州 450003

河南大学人民医院河南省人民医院生殖中心河南省生殖医院,河南郑州 450003

宫腔内人工授精 男性 肥胖 前向运动精子总数 妊娠结局

河南省高层次人才国际化培养资助项目河南省自然科学基金河南省医学科技攻关计划省部共建项目

豫科[2022]3号232300421283SBGJ202303012

2024

中华实用诊断与治疗杂志
中华预防医学会 河南省人民医院

中华实用诊断与治疗杂志

CSTPCD
影响因子:1.276
ISSN:1674-3474
年,卷(期):2024.38(2)
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