Research progress of the diagnosis and therapy of left ventricular thrombus
Left ventricular thrombus(LVT)is a severe complication of acute myocardial infarction and non-ischemic heart diseases.The major clinical diagnostic basis of LVT includes thrombotic occupying lesion in left ventricle suggested by medical history,echocardiography and/or cardiac magnetic resonance imaging.In recent years,with the development of radiological technology,the diagnostic sensitivity and accuracy of LVT have been significantly improved.The majority of specialist consensus and guidelines have recommended vitamin K antagonists,represented by warfarin,as the first-line treatment medication of LVT after acute myocardial infarction.However,several studies showed that the efficacy and safety of directed oral anticoagulants as rivaroxaban and apixaban for LVT prevention and treatment are even better than warfarin.Currently,there is lack of high-level evidence-based guidelines and specialist consensus for prevention and treatment of LVT in non-ischemic heart diseases.This paper reviews the research progress of the epidemiology,mechanisms,diagnostic methods,and anticoagulant option of LVT.
left ventricular thrombusacute myocardial infarctionnon-ischemic heart diseasesvitamin K antagonistsdirected oral anticoagulants
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