Mesenchymal stem cell-derived exosomes in the treatment of chronic neurodegenerative diseases
Chronic neurodegenerative diseases(CND)are characterized by the progressive degeneration and eventual death of neurons,with a long course and a poor prognosis,and it lacks effective treatments.As a novel type of extracellular vesicle structure,mesenchymal stem cell-derived exosomes(MSC-Exo)play an important role in promoting neuronal regeneration and repair,regulating anti-inflammation and immune responses,promoting cell survival,and reducing apoptosis,and they show a great potential in the treatment of CND.This paper reviews the research progress of MSC-Exo in the treatment of CND.