Role of lactylation in inflammatory reaction and carcinogenesis
Lactate is a crucial participant in glucose metabolism,engaging in glycolysis and serving as a substrate for energy synthesis,while also functioning as a signaling molecule.Furthermore,lactylation,an emerging post-translational modification,is regulated by lactate and glycolysis,and significantly contributes to a wide array of physiological and pathological phenomena.This paper reviews the research progress of intricate molecular mechanisms underlying protein lactylation and its consequential impact on inflammatory reaction and carcinogenesis.
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