Research progress of laboratory diagnostic methods for brucellosis
Brucellosis is a zoonotic infectious disease.Although the mortality rate of brucellosis is low,it has a tendency of chronic progression and can lead to disability and seriously affect the quality of life if it is not diagnosed and treated timely.Early and accurate diagnosis of brucellosis is difficult due to its non-specific clinical manifestations,long bacterial culture cycle and complex serological diagnosis methods.At present,laboratory diagnostic methods for brucellosis include bacterial culture(the gold diagnostic standard),serological detection,and molecular biological methods.Each diagnostic method has its own advantages,disadvantages,and applicability.This paper reviews the research progress of laboratory diagnostic methods for brucellosis.