Objective To analyze the clinical data of a patient with benign phyllodes tumor of the breast and to explore its clinical characteristics.Methods A female patient visited Jiading Branch Hospital of Shanghai General Hospital with the chief complaints of"right breast painless mass for 11 d"on October 11,2023.At 9 o'clock outside the right breast,about 2 cm from the nipple,there was a tumor,tough and hard,with clear boundary and moderate motion,and no enlarged lymph nodes in the armpit and the supraclavicular area.Breast ultrasonography showed BI-RADS 5,and mammography indicated BI-RADS 4c.Both the lipid-pressure and diffusion-weighted imaging sequences of MRI T2WI showed high signals,and the enhanced scan showed greatly continuous enhancement,without obvious cystic degeneration and necrosis,suggesting BI-RADS 4c.By day 3 after admission,the patient was performed surgery under general anesthesia,and was subjected to postsurgical routine histopathologic examination and follow-up afterwards.Results During surgery,the boundary of the mass was clear,with an intact capsule and no invasion of the pectoralis major muscle fascia or skin.The gland was separated 20 mm away from the periphery of the mass,and the mass and partial normal glands were completely removed.The postsurgical histopathology showed the mass had an intact capsule,with greyish-white and tough section.Light microscopy showed that the tumor was composed of proliferating mesenchymal and epithelial cells,with lobulated structures and epithelioid fissures visible.Mesenchymal cell proliferation was spindle shaped,with low atypia,varying density,no necrosis,rare nuclear division and no pathologic nuclear division.Immunohistochemistry showed CK5/6(partially+),P63(+),estrogen receptor(+),progesterone receptor(+),CD34(partially+),and Ki-67(mesenchymal 10％to 15％+).The patient was finally diagnosed with benign phyllodes tumor of the right breast.The patient got primary healing 10 d after surgery,with a good recovery and no related complications.A follow-up of breast ultrasonography showed no abnormalities after 6 months.Conclusions This patient with benign phyllodes tumor of the breast is clinically presented with painless,and lobulated structures.The lipid-pressure and diffusion-weighted imaging sequences of MRI T2WI show high signals,and the enhanced scan shows continuous enhancement.No obvious cystic change or necrosis is observed.The complete removal of mass achieves a safe and effective result,with no short-term recurrence.
phyllodes tumor of the breastbenignimage featureshistopathologic features
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