慢性阻塞性肺疾病合并骨质疏松发病机制及治疗研究进展
Pathogenesis and treatment of chronic obstructive pulmonary disease complicated with osteoporosis
刘珈彤 1李轶 1陈敏 1赵一凡 2赵丽敏3
作者信息
- 1. 郑州大学人民医院河南省人民医院呼吸与危重症医学科,河南郑州 450003
- 2. 河南大学人民医院河南省人民医院呼吸与危重症医学科,河南郑州 450003
- 3. 河南省人民医院呼吸与危重症医学科郑州大学人民医院,河南郑州 450003
- 折叠
摘要
慢性阻塞性肺疾病(COPD)是一种常见且进行性加重的呼吸系统疾病,病死率高.骨质疏松是其常见合并症之一,影响COPD患者生命质量,延长病程,由于其发病隐匿,诊断率和治疗率均较低.骨质疏松发病机制复杂,可能与COPD患者慢性炎症、长期使用糖皮质激素、吸烟史及营养不良等因素相关.本文就COPD合并骨质疏松的发病机制、与肺功能的关系、筛查和治疗的研究进展作一综述.
Abstract
Chronic obstructive pulmonary disease(COPD)is a common and progressive aggravation of the respiratory system,with a high mortality rate.As one of the common comorbidities,osteoporosis affects the quality of life of patients with COPD,and prolongs the course of COPD.Due to its insidious onset,the diagnostic and therapeutic rates are low.The pathogenesis of osteoporosis is complex and it may be closely correlated with the factors as chronic inflammation,long-term use of glucocorticoid,smoking history and malnutrition in COPD patients.This paper reviews the research progress of the pathogenesis of osteoporosis,its relationship with lung function,screening and treatment in COPD patients.
关键词
慢性阻塞性肺疾病/骨质疏松/肺功能Key words
chronic obstructive pulmonary disease/osteoporosis/lung function引用本文复制引用
出版年
2024
NETL
NSTL
万方数据