摘要
目的 了解甘肃省 2019 年子宫体癌发病死亡情况,分析流行特征以及 2010-2019 年发病死亡变化趋势.方法 利用甘肃省肿瘤登记中心质控合格的数据,计算子宫体癌城乡、年龄别发病(死亡)率、中标率、世标率、累积率、粗发病(死亡)率、构成比和顺位、平均年度变化百分比(AAPC)等指标.结果 2019 年甘肃省子宫体癌在女性恶性肿瘤发病率中排名第七,粗发病率 4.43/10 万,中标率 3.28/10 万,世标率 3.19/10 万.2019 甘肃省子宫体癌在女性恶性肿瘤死亡率中排名第六,粗死亡率 0.56/10 万,中标率 0.36/10 万,世标率 0.35/10 万.发病(死亡)高峰在 50~54 岁年龄段.2010-2019 年甘肃省子宫体癌发病总体呈上升趋势,中标发病率AAPC=4.34%(95%CI:1.60%~7.15%),趋势有统计学意义(P<0.05);死亡呈先升后降再升再降的波动,总体呈下降趋势,中标死亡率AAPC=-11.35%(95%CI:-26.77%~7.32%),趋势无统计学意义(P>0.05),农村地区发病(死亡)率均高于城市地区.结论 甘肃省子宫体癌总体发病呈上升趋势,死亡呈下降趋势,但农村地区死亡呈上升趋势.建议在全省大力推进女性健康科普宣教,严格落实"早发现、早诊断、早治疗"综合措施,50~54 岁年龄段女性是重点防控对象,尤其是加强开展农村地区子宫体癌的早诊早治项目.
Abstract
Objective In order to determine the incidence and mortality of uterine body cancer in Gansu province in 2019,the epidemic characteristics and the change trend of incidence and death from 2010 to 2019 were analyzed.Methods The quality control qualified data in Gansu province tumor registration center were used,uterine body cancer in urban and rural,age-specific inci-dence(mortality),the China standardized rate by Chinese population,the World standardized rate by World population,cumulative rate,crude incidence(mortality),composition ratio and rank,average annual percentage change(AAPC)and other indicators were calculated.Results In 2019,uterine body cancer in Gansu province ranked the seventh in the incidence of female malignant tumors,with a crude incidence of 4.43/100,000,the China standardized incidence was 3.28/100,000,and the World standardized incidence was 3.19/100,000.In 2019,uterine body cancer in Gansu province ranked the sixth among the mortality of female malignant tumors,with the crude mortality of 0.56/100,000,the China standardized mortality was 0.36/100,000,and the World standardized mortality was 0.35/100,000.The peak of morbidity(mortality)was in the age range of 50 to 54 years old.From 2010 to 2019,the incidence of uterine body cancer in Gansu province showed an overall upward trend.The China standardized incidence was AAPC=4.34%(95%CI:1.60%-7.15%),with a statistically significant trend(P<0.05);The mortality of uterine body cancer showed a fluctuating pat-tern of first rising,then decreasing,and increasing again,showing an overall downward trend.The China standardized mortality was AAPC=-11.35%(95%CI:-26.77%-7.32%),and the trend was not statistically significant(P>0.05).The incidence(mortali-ty)in rural areas was higher than that in urban areas.Conclusion The overall incidence of uterine body cancer in Gansu province is on the rise,and the death is on the decline.However,mortality in rural areas is on the rise.It is recommended to vigorously promote women′s health science popularization and education throughout the province,strictly implement the comprehensive measures of"early detection,early diagnosis,early treatment",and focus on the prevention and control of women aged 50-54,especially strengthening the early diagnosis and treatment of uterine body cancer in rural areas.