Research progress of signal pathways related to the anti-tumor effect of Astragalin
Astragalin is a natural flavonoid,which is known for its diverse pharmacological applications such as anti-tumor.The many studies have found that Astragalin has great anti-tumor potential by regulating PI3K/Akt signal pathway,MAPKs signal pathway,JAK/STAT signal pathway,NF-κ B signal pathway,Notch1 pathway,microRNA expression,tumor invasion and metastasis.This article reviews the literature reports on anti-tumor signal pathway of Astragalin in recent years,analyzes and summarizes the pos-sible mechanisms by which each pathway induces tumor cell apoptosis,in order to provide experimental and theoretical basis for the development and utilization of Astragalin in anti-tumor signal pathways.
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