摘要
毛钩藤碱是从传统中药钩藤中提取的吲哚生物碱,已经展现出了丰富的药理活性,包括降压、抗感染和心脏保护等.在宫颈癌、乳腺癌和结肠癌等恶性肿瘤中,毛钩藤碱通过调控细胞凋亡、免疫调节等多种途径产生抗肿瘤效果,为毛钩藤碱在癌症治疗领域的应用奠定了基础.本文通过梳理国内外相关文献,阐述毛钩藤碱在抗肿瘤方面的研究进展,为癌症治疗提供新的思路和策略.
Abstract
Hirsutine,an indole alkaloid extracted from the traditional Chinese herb Uncaria,has exhibits diverse pharmaco-logical activities,including antihypotensive,antiinfective,and cardioprotection.In cervical cancer,breast cancer,colon cancer,and oth-er malignant tumors,hirsutine has effects on anti-tumor by regulating cell apoptosis,immune regulation and other pathways,laying the foundation for the application of hirsutine in the field of cancer therapy.This article reviews relevant literature both domestically and internationally to elucidate the research progress of hirsutine in anti-tumor therapy,providing new ideas and strategies for cancer treat-ment.
基金项目
黑龙江省普通高等学校青年创新人才培养计划项目(UNPYSCT-2020222)
NETL
NSTL
万方数据