Risk factors and prognosis of postoperative intraperitoneal seeding in primary liver cancer patients
Objective To investigate the risk factors and prognosis of intraperitoneal seeding after liver resection in primary liver cancer patients.Methods The clinical and follow-up data of primary liver cancer patients with intraperitoneal seeding(the intraperitoneal seed-ing group,n=28)and without intraperitoneal seeding(the intraperitoneal non-seeding group,n=294)were retrospectively collected from January 2015 to December 2021 in Xuzhou Central Hospital.The relationship between intraperitoneal seeding and clinical characteristics and the correlation between intraperitoneal seeding and overall survival were analyzed.Results There were statistically significant differ-ences in liver capsule involvement,tumor rupture and tumor differentiation between the intraperitoneal seeding and non-seeding groups(all P＜0.05).The 3-year overall survival rates of the intraperitoneal seeding and non-seeding groups were 14.7％and 59.3％,with the average overall survival time of 11.8 months and 43.4 months.The median overall survival time of the intraperitoneal seeding and non-seeding groups was 6.5 months and 52 months(P＜0.01).Conclusions Intraperitoneal seeding after liver cancer surgery is related to capsule in-volvement,tumor rupture and poor differentiation and seriously affects the overall survival of liver cancer patients.
万方数据
维普
